Intraperitoneal Implantation
Intraperitoneal Implantation - Related Videos
09:19
Intraperitoneal Injection into Adult Zebrafish
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Cited by 238 •
2010
We demonstrate intraperitoneal injection into adult zebrafish. We use a 10 μl NanoFil microsyringe controlled by a Micro4 controller and UltraMicroPump III. This demonstration includes the use of cold water as an anesthetic.
02:25
Synergistic Effect of Intracranial and Intraperitoneal Delivery of Analgesic Drugs on Thermal Pain Response in a Rat
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2025
Source: Martinez, E., et al. Intracranial Pharmacotherapy and Pain Assays in Rodents. J. Vis. Exp. (2019).This video demonstrates the intracranial administration of an analgesic drug in an anesthetized rat with a pre-implanted guide cannula in the prefrontal cortex. An additional analgesic drug is co-administered intraperitoneally. Following recovery, the rat’s thermal pain response is assessed using Hargreave’s apparatus, where paw withdrawal latency is measured to evaluate the analgesic...
07:59
Implantation of Engineered Tissue in the Rat Heart
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Cited by 4 •
2009
Here, we describe a cardiac surgical procedure to implant engineered tissue in the atrioventricular (AV)-groove of an adult Lewis rat.
03:34
Surgical Implantation of Temperature Telemetric Monitoring System in Mouse Model: A Surgical Procedure to Implant Temperature Telemetric Device to Measure Mouse Core Body Temperature
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2025
In this video, we describe a surgical procedure to implant a temperature telemetric device in a mouse model to continuously measure its core body temperature.
04:02
Fluorescence Imaging of Neuro-Immune Dynamics Using a Skull Implant
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2025
Source: Bisht, K., et al. Precise brain mapping to perform repetitive in vivo imaging of neuro-immune dynamics in mice. J. Vis. Exp. (2020)This video demonstrates fluorescence imaging of neuro-immune dynamics in a transgenic mouse with a skull implant. Vascular and neuronal stability is imaged alongside dynamic microglial changes, reflecting immune responses to neuronal activity.
FAQs
The peritoneum can affect fluid exchange, inflammation, and tissue integration around an implanted device, graft, biomaterial, or therapeutic tissue. These interactions may influence how effectively a treatment remains in contact with the peritoneal lining and how well it performs over time. Implant design and positioning therefore need to account for the biological response of this compartment.
Suitability depends on the intended therapeutic effect, the implant’s material or biological type, and its ability to remain appropriately positioned in the peritoneal cavity. Selection must also consider risks such as infection, adhesions, and injury to abdominal organs. Matching the implant with its purpose and placement requirements supports treatment effectiveness while reducing avoidable complications.
Placement determines whether an implant can maintain useful contact with the peritoneal lining or deliver treatment locally. At the same time, inflammation and tissue integration can alter the implant’s relationship with surrounding tissues. Careful positioning is therefore central to achieving the intended outcome, particularly when the treatment depends on local exposure or incorporation into tissue.
Clinicians generally access the peritoneal compartment through the abdominal wall, then position the selected implant within the cavity according to its intended function. The placement must avoid injury to abdominal organs and support stable contact or local delivery. Careful handling and positioning are important because poor placement can reduce therapeutic benefit and increase complications.
Potential uses include local drug delivery, dialysis access, tissue engineering, and experimental cell or organ transplantation. The approach is relevant when a device, graft, biomaterial, or therapeutic tissue needs to function within the abdominal compartment or interact with the peritoneal lining. The specific application determines the implant type, placement strategy, and desired biological effect.
Important concerns include infection, adhesions, injury to abdominal organs, and other complications associated with the implant or its placement. These risks can affect tissue integration, fluid exchange, and the intended therapeutic effect. In medicine and experimental research, careful implant selection and accurate positioning are therefore essential parts of designing a safe and effective intervention.