Hemisphere Lateralization

Hemisphere lateralization is the specialization of the brain’s left and right cerebral hemispheres for different functions, a principle that helps explain variation in perception, language, emotion, and behavior. This organization emerges through partly distinct neural networks, while the corpus callosum enables the hemispheres to exchange and integrate information; language is often more strongly associated with the left hemisphere, whereas visuospatial processing is often more associated with the right. In psychology, studying hemisphere lateralization supports research on cognition, attention, memory, and consciousness, and informs neuropsychological assessment and rehabilitation after brain injury or stroke. Current research emphasizes that lateralization is flexible, interactive, and not strictly divided.

Hemisphere Lateralization - Related Videos

Education

JoVE Core - Introduction to Psychology

Cerebral Hemispheres

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2024

The human brain, a complex organ, is functionally divided into two cerebral hemispheres—left and right. These hemispheres are interconnected by a structure of paramount importance, the corpus callosum. This substantial bundle of neural fibers is not just a bridge between the hemispheres but a crucial element for the brain's comprehensive functioning. It enables efficient communication between the two hemispheres, allowing each side of the brain to control and receive sensory and motor...

Research

JoVE Journal - Neuroscience

Evaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice

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Cited by 6 •

2019

We present in vivo electrophysiological recording of the local field potential (LFP) in bilateral secondary motor cortex (M2) of mice, which can be applied to evaluate hemisphere lateralization. The study revealed altered levels of synchronization between the left and right M2 in APP/PS1 mice compared to WT controls.

Repetitive Transcranial Magnetic Stimulation to the Unilateral Hemisphere of Rat Brain

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Cited by 10 •

2016

We applied repetitive transcranial magnetic stimulation (rTMS) to the unilateral hemisphere of rat brain, by placing a 25-mm figure-8 coil 1 cm lateral to the vertex on the biauricular line and angulating the coil by 45°. An in-house water cooling system was used for rTMS for more than 20 min.

Central and Divided Visual Field Presentation of Emotional Images to Measure Hemispheric Differences in Motivated Attention

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2017

This study compared central versus divided visual field presentations of emotional images to assess differences in motivated attention between the two hemispheres. The late positive potential (LPP) was recorded using electroencephalography (EEG) and event-related potentials (ERPs) methodologies to assess motivated attention.

Recording of Local Field Potential from Both Hemispheres of the Mouse Brain

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2025

This video demonstrates in vivo recording of local field potential (LFP) from bilateral M2 areas of the mouse brain. An anesthetized mouse is secured and prepared for the procedure. To record LFPs, insert microelectrodes into the target coordinates of the bilateral M2 areas, which are responsible for complex motor movements.

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