Alexander Schramm Department of Pediatric Oncology University Children's Hospital Essen Biography Publications Institution JoVE Articles Alexander Schramm has not added a biography. If you are Alexander Schramm and would like to personalize this page please email our Author Liaison for assistance. Publications Advances and Innovations in Computer-assisted Head and Neck Oncologic Surgery The Journal of Craniofacial Surgery. Jan, 2012 | Pubmed ID: 22337424 The Metallophosphodiesterase Mpped2 Impairs Tumorigenesis in Neuroblastoma Cell Cycle (Georgetown, Tex.). Feb, 2012 | Pubmed ID: 22262177 Mandible Reconstruction with Patient-specific Pre-bent Reconstruction Plates: Comparison of a Transfer Key Method to the Standard Method--results of an in Vitro Study International Journal of Computer Assisted Radiology and Surgery. Jan, 2012 | Pubmed ID: 21594568 Clinical and Radiographic Evaluation of Early Loaded Narrow Diameter Implants - 1-year Follow-up Clinical Oral Implants Research. Sep, 2011 | Pubmed ID: 22093047 MiRNA Expression Profiling Enables Risk Stratification in Archived and Fresh Neuroblastoma Tumor Samples Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2011 | Pubmed ID: 22031095 Identification of a Novel Recurrent 1q42.2-1qter Deletion in High Risk MYCN Single Copy 11q Deleted Neuroblastomas International Journal of Cancer. Journal International Du Cancer. Jul, 2011 | Pubmed ID: 21796619 Dickkopf-3 is Regulated by the MYCN-induced MiR-17-92 Cluster in Neuroblastoma International Journal of Cancer. Journal International Du Cancer. Jul, 2011 | Pubmed ID: 21796614 A Quantitative Approach to Orbital Decompression in Graves' Disease Using Computer-Assisted Surgery: A Compilation of Different Techniques and Introduction of the "Temporal Cage" Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons. Jul, 2011 | Pubmed ID: 21757273 Bone Regeneration Without Bone Grafting After Resection of a Segment of the Mandible to Treat Bisphosphonate-related Osteonecrosis of the Jaw Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons. Oct, 2011 | Pubmed ID: 21741741 High ALK Receptor Tyrosine Kinase Expression Supersedes ALK Mutation As a Determining Factor of an Unfavorable Phenotype in Primary Neuroblastoma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Aug, 2011 | Pubmed ID: 21632861 Regulatory BCL2 Promoter Polymorphism (-938C>A) is Associated with Adverse Outcome in Patients with Prostate Carcinoma International Journal of Cancer. Journal International Du Cancer. Nov, 2011 | Pubmed ID: 21207420 Polo-like Kinase 1 is a Therapeutic Target in High-risk Neuroblastoma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2011 | Pubmed ID: 21169242 The Role of Surgical Therapy in the Management of Intravenous Bisphosphonates-related Osteonecrosis of the Jaw Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics. Feb, 2011 | Pubmed ID: 20674411 The MiR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-β Pathway in Neuroblastoma Molecular Cell. Dec, 2010 | Pubmed ID: 21145484 Meta-analysis of Neuroblastomas Reveals a Skewed ALK Mutation Spectrum in Tumors with MYCN Amplification Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2010 | Pubmed ID: 20719933 Anatomy-based Surgical Concepts for Individualized Orbital Decompression Surgery in Graves Orbitopathy. I. Orbital Size and Geometry Ophthalmic Plastic and Reconstructive Surgery. Sep-Oct, 2010 | Pubmed ID: 20592636 Accurate Prediction of Neuroblastoma Outcome Based on MiRNA Expression Profiles International Journal of Cancer. Journal International Du Cancer. Nov, 2010 | Pubmed ID: 20473924 Deep Sequencing Reveals Differential Expression of MicroRNAs in Favorable Versus Unfavorable Neuroblastoma Nucleic Acids Research. Sep, 2010 | Pubmed ID: 20466808 Chromosomal and MicroRNA Expression Patterns Reveal Biologically Distinct Subgroups of 11q- Neuroblastoma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2010 | Pubmed ID: 20406844 Accurate Outcome Prediction in Neuroblastoma Across Independent Data Sets Using a Multigene Signature Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2010 | Pubmed ID: 20179214 IL-2-driven Regulation of NK Cell Receptors with Regard to the Distribution of CD16+ and CD16- Subpopulations and in Vivo Influence After Haploidentical NK Cell Infusion Journal of Immunotherapy (Hagerstown, Md. : 1997). Feb-Mar, 2010 | Pubmed ID: 20145545 Degeneration of Retinal Ganglion Cells After Optic Nerve Sheath Fenestration in an Experimental Rat Model Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society. Dec, 2009 | Pubmed ID: 19952898 A Step Towards Individualized, Anatomy-based Surgical Concepts for Orbital Decompression in Graves' Orbitopathy Orbit (Amsterdam, Netherlands). 2009 | Pubmed ID: 19839881 Xenogeneic Immunization with Human Tyrosine Hydroxylase DNA Vaccines Suppresses Growth of Established Neuroblastoma Molecular Cancer Therapeutics. Aug, 2009 | Pubmed ID: 19671753 Meta-mining of Neuroblastoma and Neuroblast Gene Expression Profiles Reveals Candidate Therapeutic Compounds Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2009 | Pubmed ID: 19435837 Carotid Artery Stenting: Do Procedural Complications Relate to the Side Intervened Upon?: Results from the Carotid Artery Stent (CAS)-Registry of the Arbeitsgemeinschaft Leitende Kardiologische Krankenhausärzte (ALKK) Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions. Jul, 2009 | Pubmed ID: 19360877 Reanalysis of Neuroblastoma Expression Profiling Data Using Improved Methodology and Extended Follow-up Increases Validity of Outcome Prediction Cancer Letters. Sep, 2009 | Pubmed ID: 19349112 Lysine-specific Demethylase 1 is Strongly Expressed in Poorly Differentiated Neuroblastoma: Implications for Therapy Cancer Research. Mar, 2009 | Pubmed ID: 19223552 The Low-affinity Neurotrophin Receptor, P75, is Upregulated in Ganglioneuroblastoma/ganglioneuroma and Reduces Tumorigenicity of Neuroblastoma Cells in Vivo International Journal of Cancer. Journal International Du Cancer. May, 2009 | Pubmed ID: 19142969 MicroRNAs in the Pathogenesis of Neuroblastoma Cancer Letters. Feb, 2009 | Pubmed ID: 18639376 Speech and Swallowing Impairment After Treatment for Oral and Oropharyngeal Cancer Archives of Otolaryngology--head & Neck Surgery. Dec, 2008 | Pubmed ID: 19075126 Expression of the TrkA or TrkB Receptor Tyrosine Kinase Alters the Double-strand Break (DSB) Repair Capacity of SY5Y Neuroblastoma Cells DNA Repair. Oct, 2008 | Pubmed ID: 18678285 Intraoperative Navigation Assisted Reconstruction of a Maxillo-facial Gunshot Wound Oral and Maxillofacial Surgery. Dec, 2008 | Pubmed ID: 18654804 Computer-assisted Navigation in Craniomaxillofacial Tumors The Journal of Craniofacial Surgery. Jul, 2008 | Pubmed ID: 18650734 Transcription Factor AP2alpha (TFAP2a) Regulates Differentiation and Proliferation of Neuroblastoma Cells Cancer Letters. Nov, 2008 | Pubmed ID: 18620802 CADM1 is a Strong Neuroblastoma Candidate Gene That Maps Within a 3.72 Mb Critical Region of Loss on 11q23 BMC Cancer. 2008 | Pubmed ID: 18559103 Complication of Intraoral Procedures in Patients with Vascular Tumors The Journal of Craniofacial Surgery. May, 2008 | Pubmed ID: 18520405 Transient Myopia As a Complication After Complex Orbital Reconstructions with Computer-assisted Navigation Surgery Plastic and Reconstructive Surgery. May, 2008 | Pubmed ID: 18453940 Targeting the Phosphoinositide 3-kinase Isoform P110delta Impairs Growth and Survival in Neuroblastoma Cells Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2008 | Pubmed ID: 18281552 Keratoepithelin Reverts the Suppression of Tissue Factor Pathway Inhibitor 2 by MYCN in Human Neuroblastoma: a Mechanism to Inhibit Invasion International Journal of Oncology. Jan, 2008 | Pubmed ID: 18097563 Identification of 2 Putative Critical Segments of 17q Gain in Neuroblastoma Through Integrative Genomics International Journal of Cancer. Journal International Du Cancer. Mar, 2008 | Pubmed ID: 17973261 MYCN Regulates Oncogenic MicroRNAs in Neuroblastoma International Journal of Cancer. Journal International Du Cancer. Feb, 2008 | Pubmed ID: 17943719 ArrayCGH-based Classification of Neuroblastoma into Genomic Subgroups Genes, Chromosomes & Cancer. Dec, 2007 | Pubmed ID: 17823929 3D Visualization and Simulation of Frontoorbital Advancement in Metopic Synostosis Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery. Nov, 2007 | Pubmed ID: 17701413 A New System for Computer-aided Preoperative Planning and Intraoperative Navigation During Corrective Jaw Surgery IEEE Transactions on Information Technology in Biomedicine : a Publication of the IEEE Engineering in Medicine and Biology Society. May, 2007 | Pubmed ID: 17521077 Comparison of In-hospital Outcomes of Patients with Versus Without Previous Carotid Endarterectomy Undergoing Carotid Stenting (from the German ALKK CAS Registry) The American Journal of Cardiology. May, 2007 | Pubmed ID: 17478159 Fractalkine (CX3CL1)- and Interleukin-2-enriched Neuroblastoma Microenvironment Induces Eradication of Metastases Mediated by T Cells and Natural Killer Cells Cancer Research. Mar, 2007 | Pubmed ID: 17332365 Translating Expression Profiling into a Clinically Feasible Test to Predict Neuroblastoma Outcome Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2007 | Pubmed ID: 17332289 Arteriovenous Malformation of the Mandible: a Life-threatening Situation Annals of Hematology. Jun, 2007 | Pubmed ID: 17285275 Alveolar Zygomatic Buttress: A New Donor Site for Limited Preimplant Augmentation Procedures Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons. Feb, 2007 | Pubmed ID: 17236933 Bone Formation After Sinus Augmentation with Engineered Bone Clinical Oral Implants Research. Feb, 2007 | Pubmed ID: 17224026 High Resolution Tiling-path BAC Array Deletion Mapping Suggests Commonly Involved 3p21-p22 Tumor Suppressor Genes in Neuroblastoma and More Frequent Tumors International Journal of Cancer. Journal International Du Cancer. Feb, 2007 | Pubmed ID: 17096344 Computer-assisted Reconstruction of Orbital Floor Based on Cone Beam Tomography The British Journal of Oral & Maxillofacial Surgery. Jan, 2007 | Pubmed ID: 16095777 Human Fetal Neuroblast and Neuroblastoma Transcriptome Analysis Confirms Neuroblast Origin and Highlights Neuroblastoma Candidate Genes Genome Biology. 2006 | Pubmed ID: 16989664 Angiogenic and Inflammatory Response to Biodegradable Scaffolds in Dorsal Skinfold Chambers of Mice Biomaterials. Oct, 2006 | Pubmed ID: 16769111 Keratoepithelin Suppresses the Progression of Experimental Human Neuroblastomas Cancer Research. May, 2006 | Pubmed ID: 16707457 Identification of a Set of Seven Genes for the Monitoring of Minimal Residual Disease in Pediatric Acute Myeloid Leukemia Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2006 | Pubmed ID: 16638849 The Ameloblastic Fibroodontoma of the Maxilla: Case Report of a Child with Schimmelpenning-Feuerstein-Mims Syndrome/skin-eye-brain-heart Syndrome Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons. Mar, 2006 | Pubmed ID: 16487818 Navigational Maxillofacial Surgery Using Virtual Models World Journal of Surgery. Dec, 2005 | Pubmed ID: 16311844 Prediction of Clinical Outcome and Biological Characterization of Neuroblastoma by Expression Profiling Oncogene. Nov, 2005 | Pubmed ID: 16103881 Phox2B Mutations and the Delta-Notch Pathway in Neuroblastoma Cancer Letters. Oct, 2005 | Pubmed ID: 16084642 Gains and Overexpression Identify DEK and E2F3 As Targets of Chromosome 6p Gains in Retinoblastoma Oncogene. Sep, 2005 | Pubmed ID: 16007192 Application of Microarray-based Technology to Neuroblastoma Cancer Letters. Oct, 2005 | Pubmed ID: 15951106 Biological Effects of TrkA and TrkB Receptor Signaling in Neuroblastoma Cancer Letters. Oct, 2005 | Pubmed ID: 15921851 Identification of Dynamic Proteome Changes Upon Ligand Activation of Trk-receptors Using Two-dimensional Fluorescence Difference Gel Electrophoresis and Mass Spectrometry Molecular & Cellular Proteomics : MCP. Mar, 2005 | Pubmed ID: 15654083 Microarray Analysis Reveals Differential Gene Expression Patterns and Regulation of Single Target Genes Contributing to the Opposing Phenotype of TrkA- and TrkB-expressing Neuroblastomas Oncogene. Jan, 2005 | Pubmed ID: 15637590 High Activin A-expression in Human Neuroblastoma: Suppression of Malignant Potential and Correlation with Favourable Clinical Outcome Oncogene. Jan, 2005 | Pubmed ID: 15580313 The Phox2B Homeobox Gene is Mutated in Sporadic Neuroblastomas Oncogene. Dec, 2004 | Pubmed ID: 15516980 Distraction Osteogenesis in an Anterior Mandibular Bone Defect Utilizing Lingual Periosteal Release: a Case Report The International Journal of Oral & Maxillofacial Implants. Sep-Oct, 2004 | Pubmed ID: 15508994 Navigation-aided Reconstruction of Medial Orbital Wall and Floor Contour in Cranio-maxillofacial Reconstruction Injury. Oct, 2004 | Pubmed ID: 15351656 Structure and Function of a Regulated Archaeal Triosephosphate Isomerase Adapted to High Temperature Journal of Molecular Biology. Sep, 2004 | Pubmed ID: 15342242 Neuronavigation-assisted Cranial Reconstruction Neurosurgery. Jul, 2004 | Pubmed ID: 15214985 Computer-assisted Reconstruction of the Facial Skeleton Archives of Facial Plastic Surgery : Official Publication for the American Academy of Facial Plastic and Reconstructive Surgery, Inc. and the International Federation of Facial Plastic Surgery Societies. Sep-Oct, 2003 | Pubmed ID: 12975145 Color Duplex Sonography for the Monitoring of Vascularized Free Bone Flaps Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery. Jul, 2003 | Pubmed ID: 12869920 Distraction Osteogenesis and Tissue Engineering--new Options for Enhancing the Implant Site The International Journal of Periodontics & Restorative Dentistry. Jun, 2003 | Pubmed ID: 12854780 Characteristics of Oral Cancer in a Central European Population: Defining the Dentist's Role Journal of the American Dental Association (1939). Mar, 2003 | Pubmed ID: 12699044 Maxillary Sinus Floor Augmention with Autogenous Bone Grafts to Enable Placement of SLA-surfaced Implants: Preliminary Results After 15-40 Months Clinical Oral Implants Research. Apr, 2003 | Pubmed ID: 12656881 Follow-up of Condylar Fractures of the Mandible in 8 Patients at 18 Months After Transoral Endoscopic-assisted Open Treatment Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons. Jan, 2003 | Pubmed ID: 12524608 Computer-aided Procedures in Implantology, Distraction and Cranio-maxillofacial Surgery Annals of the Royal Australasian College of Dental Surgeons. Oct, 2002 | Pubmed ID: 14507131 Navigation-guided Resection of Temporomandibular Joint Ankylosis Promotes Safety in Skull Base Surgery Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons. Nov, 2002 | Pubmed ID: 12420260 Computer-assisted Secondary Reconstruction of Unilateral Posttraumatic Orbital Deformity Plastic and Reconstructive Surgery. Nov, 2002 | Pubmed ID: 12409759 Quantification of the Neurodegenerative Impact on the Visual System Following Sudden Retrobulbar Expanding Lesions - an Experimental Model Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery. Aug, 2002 | Pubmed ID: 12231204 Pain, Function, and Psychologic Outcome Before, During, and After Intraoral Tumor Resection Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons. Jul, 2002 | Pubmed ID: 12089691 Follow-up in Patients with Oral Cancer Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons. Apr, 2002 | Pubmed ID: 11928093 Expression Analysis of Pediatric Solid Tumor Cell Lines Using Oligonucleotide Microarrays International Journal of Oncology. Mar, 2002 | Pubmed ID: 11836553 Production of Chick Embryo Extract for the Cultivation of Murine Neural Crest Stem Cells Kristian Pajtler*1, Anna Bohrer*1, Jochen Maurer2, Hubert Schorle2, Alexander Schramm1, Angelika Eggert1, Johannes Hubertus Schulte1 1Department of Pediatric Oncology, University Children's Hospital Essen, 2Department of Developmental Pathology, Bonn Medical School, Institute of Pathology JoVE 2380 Neuroscienze
Production of Chick Embryo Extract for the Cultivation of Murine Neural Crest Stem Cells Kristian Pajtler*1, Anna Bohrer*1, Jochen Maurer2, Hubert Schorle2, Alexander Schramm1, Angelika Eggert1, Johannes Hubertus Schulte1 1Department of Pediatric Oncology, University Children's Hospital Essen, 2Department of Developmental Pathology, Bonn Medical School, Institute of Pathology JoVE 2380 Neuroscienze