Iman Osman

Publications

• The Histone Demethylase PHF8 Regulates TGFβ Signaling and Promotes Melanoma Metastasis
  Science Advances. Feb, 2022  |   Pubmed ID: 35179962
• Deep Learning and Pathomics Analyses Reveal Cell Nuclei As Important Features for Mutation Prediction of BRAF-Mutated Melanomas
  The Journal of Investigative Dermatology. Oct, 2021  |   Pubmed ID: 34757067
• Bacteroides Vulgatus and Bacteroides Dorei Predict Immune-related Adverse Events in Immune Checkpoint Blockade Treatment of Metastatic Melanoma
  Genome Medicine. 10, 2021  |   Pubmed ID: 34641962
• Targeting the Atf7ip-Setdb1 Complex Augments Antitumor Immunity by Boosting Tumor Immunogenicity
  Cancer Immunology Research. 11, 2021  |   Pubmed ID: 34462284
• Correction To: The Urgency of Utilizing COVID-19 Biospecimens for Research in the Heart of the Global Pandemic
  Journal of Translational Medicine. Jun, 2021  |   Pubmed ID: 34082754
• The "Great Debate" at Melanoma Bridge 2020: December, 5th, 2020
  Journal of Translational Medicine. 04, 2021  |   Pubmed ID: 33827575
• Chronic Immune-Related Adverse Events Following Adjuvant Anti-PD-1 Therapy for High-risk Resected Melanoma
  JAMA Oncology. 05, 2021  |   Pubmed ID: 33764387
• Tumor Immunogenomic Signatures Improve a Prognostic Model of Melanoma Survival
  Journal of Translational Medicine. 02, 2021  |   Pubmed ID: 33596955
• Treatment with Therapeutic Anticoagulation is Not Associated with Immunotherapy Response in Advanced Cancer Patients
  Journal of Translational Medicine. 01, 2021  |   Pubmed ID: 33516263
• Using Machine Learning Algorithms to Predict Immunotherapy Response in Patients with Advanced Melanoma
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 01, 2021  |   Pubmed ID: 33208341
• Baseline Prognostic Nutritional Index and Changes in Pretreatment Body Mass Index Associate with Immunotherapy Response in Patients with Advanced Cancer
  Journal for Immunotherapy of Cancer. 11, 2020  |   Pubmed ID: 33219093
• Revisiting the Association Between Skin Toxicity and Better Response in Advanced Cancer Patients Treated with Immune Checkpoint Inhibitors
  Journal of Translational Medicine. 11, 2020  |   Pubmed ID: 33176813
• Preliminary Analysis of Distinct Clinical and Biologic Features of Bone Metastases in Melanoma
  Melanoma Research. 10, 2020  |   Pubmed ID: 32804707
• The Urgency of Utilizing COVID-19 Biospecimens for Research in the Heart of the Global Pandemic
  Journal of Translational Medicine. 06, 2020  |   Pubmed ID: 32487093
• TERT, BRAF, and NRAS Mutational Heterogeneity Between Paired Primary and Metastatic Melanoma Tumors
  The Journal of Investigative Dermatology. 08, 2020  |   Pubmed ID: 32087194
• Melanoma Prognosis: Accuracy of the American Joint Committee on Cancer Staging Manual Eighth Edition
  Journal of the National Cancer Institute. 09, 2020  |   Pubmed ID: 31977051
• Functional Analysis of RPS27 Mutations and Expression in Melanoma
  Pigment Cell & Melanoma Research. 05, 2020  |   Pubmed ID: 31663663
• Relating the Gut Metagenome and Metatranscriptome to Immunotherapy Responses in Melanoma Patients
  Genome Medicine. 10, 2019  |   Pubmed ID: 31597568
• The Complex Relationship Between Body Mass Index and Response to Immune Checkpoint Inhibition in Metastatic Melanoma Patients
  Journal for Immunotherapy of Cancer. 08, 2019  |   Pubmed ID: 31426863
• Immunomodulatory Germline Variation Associated with the Development of Multiple Primary Melanoma (MPM)
  Scientific Reports. 07, 2019  |   Pubmed ID: 31308438
• Impact of Initial Stage on Metastatic Melanoma Survival
  Melanoma Research. 06, 2019  |   Pubmed ID: 31026246
• Autoimmune Genetic Risk Variants As Germline Biomarkers of Response to Melanoma Immune-checkpoint Inhibition
  Cancer Immunology, Immunotherapy : CII. Jun, 2019  |   Pubmed ID: 30863922
• Development of Novel Mutation-Specific Droplet Digital PCR Assays Detecting TERT Promoter Mutations in Tumor and Plasma Samples
  The Journal of Molecular Diagnostics : JMD. 03, 2019  |   Pubmed ID: 30827467
• Association Between Ki-67 Expression and Clinical Outcomes Among Patients with Clinically Node-negative, Thick Primary Melanoma Who Underwent Nodal Staging
  Journal of Surgical Oncology. Jul, 2018  |   Pubmed ID: 29878361
• Adjuvant NY-ESO-1 Vaccine Immunotherapy in High-risk Resected Melanoma: a Retrospective Cohort Analysis
  Journal for Immunotherapy of Cancer. 05, 2018  |   Pubmed ID: 29773080
• Baseline Antibody Profiles Predict Toxicity in Melanoma Patients Treated with Immune Checkpoint Inhibitors
  Journal of Translational Medicine. 04, 2018  |   Pubmed ID: 29606147
• Pre-metastatic Cancer Exosomes Induce Immune Surveillance by Patrolling Monocytes at the Metastatic Niche
  Nature Communications. 11, 2017  |   Pubmed ID: 29105655
• A Systems Biology Approach Identifies FUT8 As a Driver of Melanoma Metastasis
  Cancer Cell. 06, 2017  |   Pubmed ID: 28609658
• Outcomes in Melanoma Patients Treated with BRAF/MEK-Directed Therapy or Immune Checkpoint Inhibition Stratified by Clinical Trial Versus Standard of Care
  Oncology. 2017  |   Pubmed ID: 28601879
• Genetic Markers of Pigmentation Are Novel Risk Loci for Uveal Melanoma
  Scientific Reports. Aug, 2016  |   Pubmed ID: 27499155
• Constitutive Lck Activity Drives Sensitivity Differences Between CD8+ Memory T Cell Subsets
  Journal of Immunology (Baltimore, Md. : 1950). 07, 2016  |   Pubmed ID: 27271569
• De Novo Vs Nevus-Associated Melanomas: Differences in Associations With Prognostic Indicators and Survival
  Journal of the National Cancer Institute. 10, 2016  |   Pubmed ID: 27235387
• Pathways for Modulating Exosome Lipids Identified By High-Density Lipoprotein-Like Nanoparticle Binding to Scavenger Receptor Type B-1
  Scientific Reports. Mar, 2016  |   Pubmed ID: 26964503
• The Expression Quantitative Trait Loci in Immune Pathways and Their Effect on Cutaneous Melanoma Prognosis
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 07, 2016  |   Pubmed ID: 26733611
• Identification of a Novel Pathogenic Germline KDR Variant in Melanoma
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 05, 2016  |   Pubmed ID: 26631613
• Sensitivity of Plasma BRAFmutant and NRASmutant Cell-free DNA Assays to Detect Metastatic Melanoma in Patients with Low RECIST Scores and Non-RECIST Disease Progression
  Molecular Oncology. Jan, 2016  |   Pubmed ID: 26440707
• Phosphorylation of EIF2α Triggered by MTORC1 Inhibition and PP6C Activation is Required for Autophagy and is Aberrant in PP6C-mutated Melanoma
  Science Signaling. Mar, 2015  |   Pubmed ID: 25759478
• Genetic Associations of the Interleukin Locus at 1q32.1 with Clinical Outcomes of Cutaneous Melanoma
  Journal of Medical Genetics. Apr, 2015  |   Pubmed ID: 25604082
• RSK1 Activation Promotes Invasion in Nodular Melanoma
  The American Journal of Pathology. Mar, 2015  |   Pubmed ID: 25579842
• Melanoma Expression of Matrix Metalloproteinase-23 is Associated with Blunted Tumor Immunity and Poor Responses to Immunotherapy
  Journal of Translational Medicine. Dec, 2014  |   Pubmed ID: 25491880