Kerensa Broersen Department of Applied Stem Cell Technologies, TechMed Centre Enschede University of Twente Biography Publications Institution JoVE Articles Kerensa Broersen has not added a biography. If you are Kerensa Broersen and would like to personalize this page please email our Author Liaison for assistance. Publications Alzheimer's Disease: Treatment Strategies and Their Limitations International Journal of Molecular Sciences. Nov, 2022 | Pubmed ID: 36430432 Use of Standard U-bottom and V-bottom Well Plates to Generate Neuroepithelial Embryoid Bodies PloS One. 2022 | Pubmed ID: 35536781 Engineering Organoids for Modeling of Phenylketonuria Frontiers in Molecular Neuroscience. 2021 | Pubmed ID: 35082602 A Review of Oxidative Stress Products and Related Genes in Early Alzheimer's Disease Journal of Alzheimer's Disease : JAD. 2021 | Pubmed ID: 34420962 Cross-seeding of Alpha-synuclein Aggregation by Amyloid Fibrils of Food Proteins The Journal of Biological Chemistry. 2021 | Pubmed ID: 33539920 Plant Isoquinoline Alkaloids As Potential Neurodrugs: A Comparative Study of the Effects of Benzo[c]phenanthridine and Berberine-based Compounds on β-amyloid Aggregation Chemico-biological Interactions. Jan, 2021 | Pubmed ID: 33098838 Milk Processing Affects Structure, Bioavailability and Immunogenicity of β-lactoglobulin Foods (Basel, Switzerland). Jul, 2020 | Pubmed ID: 32635246 Exposure of a Cryptic Hsp70 Binding Site Determines the Cytotoxicity of the ALS-associated SOD1-mutant A4V Protein Engineering, Design & Selection : PEDS. Dec, 2019 | Pubmed ID: 32399571 Molecular Mechanisms and Genetics of Oxidative Stress in Alzheimer's Disease Journal of Alzheimer's Disease : JAD. 2019 | Pubmed ID: 31744008 Apolipoprotein E Associated with Reconstituted High-density Lipoprotein-like Particles is Protected from Aggregation FEBS Letters. Jun, 2019 | Pubmed ID: 31058310 Benzodifurans for Biomedical Applications: BZ4, a Selective Anti-proliferative and Anti-amyloid Lead Compound Future Medicinal Chemistry. Feb, 2019 | Pubmed ID: 30801198 Searching for Improved Mimetic Peptides Inhibitors Preventing Conformational Transition of Amyloid-β Monomer Bioorganic Chemistry. Dec, 2018 | Pubmed ID: 30144634 Structural and Aggregation Properties of Alpha-Synuclein Linked to Phospholipase A2 Action Protein and Peptide Letters. 2018 | Pubmed ID: 29577851 Optimized Triton X-114 Assisted Lipopolysaccharide (LPS) Removal Method Reveals the Immunomodulatory Effect of Food Proteins PloS One. 2017 | Pubmed ID: 28355240 Characterization of Insulin-degrading Enzyme-mediated Cleavage of Aβ in Distinct Aggregation States Biochimica Et Biophysica Acta. Jun, 2016 | Pubmed ID: 26968463 Could Ecosystem Management Provide a New Framework for Alzheimer's Disease? Alzheimer's & Dementia : the Journal of the Alzheimer's Association. Jan, 2016 | Pubmed ID: 26341147 Two Distinct β-sheet Structures in Italian-mutant Amyloid-beta Fibrils: a Potential Link to Different Clinical Phenotypes Cellular and Molecular Life Sciences : CMLS. Dec, 2015 | Pubmed ID: 26190022 New Mimetic Peptides Inhibitors of Αβ Aggregation. Molecular Guidance for Rational Drug Design European Journal of Medicinal Chemistry. May, 2015 | Pubmed ID: 25805447 A Comparative Analysis of the Aggregation Behavior of Amyloid-β Peptide Variants FEBS Letters. Nov, 2012 | Pubmed ID: 23103738 Molecular Plasticity Regulates Oligomerization and Cytotoxicity of the Multipeptide-length Amyloid-β Peptide Pool The Journal of Biological Chemistry. Oct, 2012 | Pubmed ID: 22992745 The Mechanism of γ-Secretase Dysfunction in Familial Alzheimer Disease The EMBO Journal. May, 2012 | Pubmed ID: 22505025 Structural Basis for Increased Toxicity of Pathological Aβ42:aβ40 Ratios in Alzheimer Disease The Journal of Biological Chemistry. Feb, 2012 | Pubmed ID: 22157754 Neurotoxicity of Alzheimer's Disease Aβ Peptides is Induced by Small Changes in the Aβ42 to Aβ40 Ratio The EMBO Journal. Oct, 2010 | Pubmed ID: 20818335 Robust vevsfabrikasjon for langsiktig kultur av iPSC-avledede hjerneorganoider for aldringsforskning Lena Sophie Koch1, David Choy Buentello2,3, Kerensa Broersen1 1Department of Applied Stem Cell Technologies, TechMed Centre Enschede, University of Twente, 2Centro de Biotecnología-FEMSA, Tecnologico de Monterrey, 3Department of Genetics, Harvard Medical School JoVE 64586 Neuroscienze
Robust vevsfabrikasjon for langsiktig kultur av iPSC-avledede hjerneorganoider for aldringsforskning Lena Sophie Koch1, David Choy Buentello2,3, Kerensa Broersen1 1Department of Applied Stem Cell Technologies, TechMed Centre Enschede, University of Twente, 2Centro de Biotecnología-FEMSA, Tecnologico de Monterrey, 3Department of Genetics, Harvard Medical School JoVE 64586 Neuroscienze