Lucía Nuñez Departamento de Bioquìmica y Biologìa Molecular y Fisiologìa Universidad de Valladolid Biography Publications Institution JoVE Articles Lucía Nuñez has not added a biography. If you are Lucía Nuñez and would like to personalize this page please email our Author Liaison for assistance. Publications Non-steroidal Anti-inflammatory Drugs (NSAIDs) and Neuroprotection in the Elderly: a View from the Mitochondria Neural Regeneration Research. Sep, 2015 | Pubmed ID: 26604882 Single-Cell Phenotypic Characterization of Human Pituitary GHomas and Non-Functioning Adenomas Based on Hormone Content and Calcium Responses to Hypothalamic Releasing Hormones Frontiers in Oncology. 2015 | Pubmed ID: 26106585 Susceptibility to Excitotoxicity in Aged Hippocampal Cultures and Neuroprotection by Non-steroidal Anti-inflammatory Drugs: Role of Mitochondrial Calcium Journal of Neurochemistry. Feb, 2015 | Pubmed ID: 25492611 Calcium Imaging in Neuron Cell Death Methods in Molecular Biology (Clifton, N.J.). 2015 | Pubmed ID: 25431058 A Reciprocal Shift in Transient Receptor Potential Channel 1 (TRPC1) and Stromal Interaction Molecule 2 (STIM2) Contributes to Ca2+ Remodeling and Cancer Hallmarks in Colorectal Carcinoma Cells The Journal of Biological Chemistry. Oct, 2014 | Pubmed ID: 25143380 Functional Characterization of a Novel Frameshift Mutation in the C-terminus of the Nav1.5 Channel Underlying a Brugada Syndrome with Variable Expression in a Spanish Family PloS One. 2013 | Pubmed ID: 24363796 Intracellular Ca(2+) Remodeling During the Phenotypic Journey of Human Coronary Smooth Muscle Cells Cell Calcium. Nov, 2013 | Pubmed ID: 24079969 Somatic MYH7, MYBPC3, TPM1, TNNT2 and TNNI3 Mutations in Sporadic Hypertrophic Cardiomyopathy Circulation Journal : Official Journal of the Japanese Circulation Society. 2013 | Pubmed ID: 23782526 P.D1690N Nav1.5 Rescues P.G1748D Mutation Gating Defects in a Compound Heterozygous Brugada Syndrome Patient Heart Rhythm : the Official Journal of the Heart Rhythm Society. Feb, 2013 | Pubmed ID: 23085483 Regulation of Mitochondrial Permeability Transition Pore by PINK1 Molecular Neurodegeneration. 2012 | Pubmed ID: 22630785 Study of Neurotoxic Intracellular Calcium Signalling Triggered by Amyloids Methods in Molecular Biology (Clifton, N.J.). 2012 | Pubmed ID: 22528098 Increased Production of Soluble TLR2 by Lamina Propria Mononuclear Cells from Ulcerative Colitis Patients Immunobiology. Jun, 2012 | Pubmed ID: 22101184 Calcium Microdomains at the Immunological Synapse: How ORAI Channels, Mitochondria and Calcium Pumps Generate Local Calcium Signals for Efficient T-cell Activation The EMBO Journal. Oct, 2011 | Pubmed ID: 21847095 Soluble ST2: a New and Promising Activity Marker in Ulcerative Colitis World Journal of Gastroenterology. May, 2011 | Pubmed ID: 21633527 Irvalec Inserts into the Plasma Membrane Causing Rapid Loss of Integrity and Necrotic Cell Death in Tumor Cells PloS One. 2011 | Pubmed ID: 21556352 Nonsteroidal Anti-inflammatory Drugs Inhibit Vascular Smooth Muscle Cell Proliferation by Enabling the Ca2+-dependent Inactivation of Calcium Release-activated Calcium/orai Channels Normally Prevented by Mitochondria The Journal of Biological Chemistry. May, 2011 | Pubmed ID: 21402693 Phosphatidylinositol 3-kinase Interacts with the Glucocorticoid Receptor Upon TLR2 Activation Journal of Cellular and Molecular Medicine. Feb, 2011 | Pubmed ID: 19874421 Novel Human Pathological Mutations. Gene Symbol: MYBPC3. Disease: Cardiomyopathy, Hypertrophic Human Genetics. Apr, 2010 | Pubmed ID: 21488308 Novel Human Pathological Mutations. Gene Symbol: MYBPC3. Disease: Cardiomyopathy, Hypertrophic Human Genetics. Apr, 2010 | Pubmed ID: 21488307 Novel Human Pathological Mutations. Gene Symbol: MYBPC3. Disease: Cardiomyopathy, Hypertrophic Human Genetics. Apr, 2010 | Pubmed ID: 21488306 Novel Human Pathological Mutations. Gene Symbol: MYBPC3. Disease: Cardiomyopathy, Hypertrophic Human Genetics. Apr, 2010 | Pubmed ID: 21488259 Insights into Genotype-phenotype Correlation in Hypertrophic Cardiomyopathy. Findings from 18 Spanish Families with a Single Mutation in MYBPC3 Heart (British Cardiac Society). Dec, 2010 | Pubmed ID: 21088121 Screening Mutations in Myosin Binding Protein C3 Gene in a Cohort of Patients with Hypertrophic Cardiomyopathy BMC Medical Genetics. 2010 | Pubmed ID: 20433692 17beta-estradiol Promotes Cementoblast Proliferation and Cementum Formation in Experimental Periodontitis Journal of Periodontology. Jul, 2010 | Pubmed ID: 20214440 Characterization of the Novel ST2/IL-33 System in Patients with Inflammatory Bowel Disease Inflammatory Bowel Diseases. Jul, 2010 | Pubmed ID: 20014018 Functional Effects of KCNE3 Mutation and Its Role in the Development of Brugada Syndrome Circulation. Arrhythmia and Electrophysiology. Aug, 2008 | Pubmed ID: 19122847 Nitric Oxide Inhibits Kv4.3 and Human Cardiac Transient Outward Potassium Current (Ito1) Cardiovascular Research. Dec, 2008 | Pubmed ID: 18678642 Mitochondrial Ca2+ Overload Underlies Abeta Oligomers Neurotoxicity Providing an Unexpected Mechanism of Neuroprotection by NSAIDs PloS One. 2008 | Pubmed ID: 18648507 The Role of Mitochondrial Potential in Control of Calcium Signals Involved in Cell Proliferation Cell Calcium. Sep, 2008 | Pubmed ID: 18241916 Rapid Changes in Anterior Pituitary Cell Phenotypes in Male and Female Mice After Acute Cold Stress Endocrinology. May, 2008 | Pubmed ID: 18202140 Glucose Induces Synchronous Mitochondrial Calcium Oscillations in Intact Pancreatic Islets Cell Calcium. Jan, 2008 | Pubmed ID: 17499355 Lipid-lowering Therapy with Statins, a New Approach to Antiarrhythmic Therapy Pharmacology & Therapeutics. Apr, 2007 | Pubmed ID: 17287023 Bioluminescence Imaging of Mitochondrial Ca2+ Dynamics in Soma and Neurites of Individual Adult Mouse Sympathetic Neurons The Journal of Physiology. Apr, 2007 | Pubmed ID: 17234693 Genetically Engineered Mice As a Model for Studying Cardiac Arrhythmias Frontiers in Bioscience : a Journal and Virtual Library. 2007 | Pubmed ID: 17127281 Association of 14-3-3 Proteins to Beta1-adrenergic Receptors Modulates Kv11.1 K+ Channel Activity in Recombinant Systems Molecular Biology of the Cell. Nov, 2006 | Pubmed ID: 16914520 Nitric Oxide Blocks HKv1.5 Channels by S-nitrosylation and by a Cyclic GMP-dependent Mechanism Cardiovascular Research. Oct, 2006 | Pubmed ID: 16876149 Cell Proliferation Depends on Mitochondrial Ca2+ Uptake: Inhibition by Salicylate The Journal of Physiology. Feb, 2006 | Pubmed ID: 16339178 Bioluminescence Imaging of Nuclear Calcium Oscillations in Intact Pancreatic Islets of Langerhans from the Mouse Cell Calcium. Aug, 2005 | Pubmed ID: 16095687 Spironolactone and Its Main Metabolite Canrenoic Acid Block HKv1.5, Kv4.3 and Kv7.1 + MinK Channels British Journal of Pharmacology. Sep, 2005 | Pubmed ID: 15980874 Angiotensin II, Angiotensin II Antagonists and Spironolactone and Their Modulation of Cardiac Repolarization Trends in Pharmacological Sciences. Mar, 2005 | Pubmed ID: 15749161 Diltiazem Inhibits HKv1.5 and Kv4.3 Currents at Therapeutic Concentrations Cardiovascular Research. Dec, 2004 | Pubmed ID: 15537499 Phenotypic Characterization of Multi-functional Somatotropes, Mammotropes and Gonadotropes of the Mouse Anterior Pituitary Pflügers Archiv : European Journal of Physiology. Dec, 2004 | Pubmed ID: 15378370 Multifunctional Cells in Human Pituitary Adenomas: Implications for Paradoxical Secretion and Tumorigenesis The Journal of Clinical Endocrinology and Metabolism. Sep, 2004 | Pubmed ID: 15356060 Anterior Pituitary Thyrotropes Are Multifunctional Cells American Journal of Physiology. Endocrinology and Metabolism. Dec, 2004 | Pubmed ID: 15226100 Interaction of Angiotensin II with the Angiotensin Type 2 Receptor Inhibits the Cardiac Transient Outward Potassium Current Cardiovascular Research. Apr, 2004 | Pubmed ID: 15023555 Multifunctional Cells of Mouse Anterior Pituitary Reveal a Striking Sexual Dimorphism The Journal of Physiology. Jun, 2003 | Pubmed ID: 12730343 Calcium Dynamics and Resting Transcriptional Activity Regulates Prolactin Gene Expression Endocrinology. Sep, 2002 | Pubmed ID: 12193569 Redistribution of Ca2+ Among Cytosol and Organella During Stimulation of Bovine Chromaffin Cells FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Mar, 2002 | Pubmed ID: 11874983 Fluorescence and Bioluminescence Imaging of Subcellular Ca2+ in Aged Hippocampal Neurons María Calvo-Rodríguez1, Carlos Villalobos1, Lucía Nuñez2 1Instituto de Biologìa y Genética Molecular, Consejo Superior de Investigaciones Cientìficas, 2Departamento de Bioquìmica y Biologìa Molecular y Fisiologìa, Universidad de Valladolid JoVE 53330 Neuroscienze
Fluorescence and Bioluminescence Imaging of Subcellular Ca2+ in Aged Hippocampal Neurons María Calvo-Rodríguez1, Carlos Villalobos1, Lucía Nuñez2 1Instituto de Biologìa y Genética Molecular, Consejo Superior de Investigaciones Cientìficas, 2Departamento de Bioquìmica y Biologìa Molecular y Fisiologìa, Universidad de Valladolid JoVE 53330 Neuroscienze