Hybrid Wettable Pattern

A hybrid wettable pattern is an engineered surface that combines regions with different wettability, such as hydrophilic and hydrophobic areas, to control how liquids spread, stop, or move. Differences in surface energy create wettability contrasts that guide droplets through capillary forces, while boundaries can pin contact lines and define fluid pathways without moving mechanical parts. In engineering, these patterns support passive liquid handling in microfluidic devices, lab-on-a-chip systems, sensors, and surface-based manufacturing. By controlling droplet position, shape, and transport, hybrid wettable patterns can reduce system complexity, improve fluidic precision, and enable compact platforms for chemical analysis and other functional applications.

Hybrid Wettable Pattern - Related Videos

Research

JoVE Journal - Engineering

Pool-Boiling Heat-Transfer Enhancement on Cylindrical Surfaces with Hybrid Wettable Patterns

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Cited by 17 •

2017

Pool-boiling heat-transfer experiments were carried out to observe the effects of hybrid wettable patterns on the heat-transfer coefficient (HTC). The parameters of investigation are the number of interlines and the pattern orientation of the modified wettable surface.

Research

JoVE Journal - Biology
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Radioactive in situ Hybridization for Detecting Diverse Gene Expression Patterns in Tissue

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Cited by 21 •

2012

This protocol is successfully used to quantitatively detect levels and spatial patterns of mRNA expression in multiple tissue types across vertebrate species. The method can detect low abundance transcripts and allows processing of hundreds of slides simultaneously. We present this protocol using expression profiling of avian embryonic brain formation as an example.

A High Throughput in situ Hybridization Method to Characterize mRNA Expression Patterns in the Fetal Mouse Lower Urogenital Tract

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Cited by 49 •

2011

Here, we describe an efficient high throughput in situ hybridization (ISH) method for visualizing patterns of mRNA expression in developing fetal mouse prostate tissue sections. The method can be easily adapted to visualize mRNA expression patterns in other mouse tissues or in tissues from other species.

Education

JoVE Science Education - Advanced Biology

Whole-Mount In Situ Hybridization

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2023

Whole-mount in situ hybridization (WMISH) is a common technique used for visualizing the location of expressed RNAs in embryos. In this process, synthetically produced RNA probes are first complementarily bound, or "hybridized," to the transcripts of target genes. Immunohistochemistry or fluorescence is then used to detect these RNA hybrids, revealing spatial and temporal patterns of gene expression. Unlike traditional in situ hybridization techniques, which require thin tissue sections whose...

Hybridization of Atomic Orbitals I

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2020

The mathematical expression known as the wave function, ψ, contains information about each orbital and the wavelike properties of electrons in an isolated atom. When atoms are bound together in a molecule, the wave functions combine to produce new mathematical descriptions that have different shapes. This process of combining the wave functions for atomic orbitals is called hybridization and is mathematically accomplished by the linear combination of atomic orbitals. The new orbitals that...

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