Segmental Ureteral Stricture
Segmental Ureteral Stricture - Related Videos
14:05
A Murine Model of Irreversible and Reversible Unilateral Ureteric Obstruction
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Cited by 47 •
2014
The murine model of irreversible unilateral ureteric obstruction (UUO) is presented together with the model of reversible UUO in which the ureteric obstruction is relieved by anastomosis of the severed ureter into the bladder. These models enable the study of renal inflammation and scarring as well as tissue remodeling.
05:57
ADSC-sheet Transplantation to Prevent Stricture after Extended Esophageal Endoscopic Submucosal Dissection
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Cited by 14 •
2017
This study reports a successful method of endoscopical adipose tissue-derived stromal cell (ADSC)-sheet transplantation for esophageal stricture prevention after an extended endoscopic submucosal dissection (ESD) in a swine model.
01:30
Esophageal Strictures-I: Introduction
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2025
Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous). Etiology The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
05:09
Urethral Stricture Induction Followed by Buccal Mucosa Graft Urethroplasty in a Rat Model
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Cited by 3 •
2023
In the present protocol, a urethral stricture induction was developed in Wistar rats, followed by urethral reconstruction with a buccal mucosa graft. A retrograde urethrogram and laser Doppler assessment were performed, validating urethral reconstruction (after stricture formation) and graft placement.
03:55
Urethroplasty with Pedicled Tunica Vaginalis for the Treatment of Long-segment Anterior Urethral Stricture Caused by Lichen Sclerosus of Glans Penis
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Cited by 1 •
2024
This article introduces a surgical method using a pedicled tunica vaginalis to treat long-segment urethral stricture resulting from lichen sclerosus. The tunica vaginalis is an excellent substitute for the urethra, leading to quick postoperative recovery for patients.
FAQs
A reduced lumen raises pressure upstream, so urine can accumulate toward the kidney and produce hydronephrosis. Persistent pressure may be accompanied by flank pain, infection, or declining renal function. The clinical concern therefore extends beyond the narrowed site: impaired drainage can threaten function of the affected kidney, particularly when the problem remains untreated.
These factors can damage or irritate ureteral tissue, after which healing may produce scar formation. Scar tissue can narrow the lumen and create a segment that restricts urine passage. Identifying the likely cause provides important context for the narrowing and helps clinicians consider anatomy, symptoms, and renal function when selecting treatment.
These features show where the ureter is affected and how much tissue is involved. That anatomical information helps clinicians assess whether a particular approach can address the narrowed segment and compare options such as stenting, balloon dilation, endoscopic incision, or reconstruction. The findings are interpreted together with the cause, symptoms, and renal function.
Evaluation commonly combines imaging with functional assessment. Imaging helps characterize the urinary tract and localize the abnormal segment, while functional information helps place the narrowing in the context of kidney performance and drainage. Together, these assessments help define the stricture’s location, length, and severity, supporting a more appropriate management decision.
Management may include ureteral stenting, balloon dilation, endoscopic incision, or reconstructive surgery. A stent can support urine passage, while dilation and incision address the narrowed area through procedural treatment. Reconstruction provides a surgical option when the anatomy, underlying cause, symptoms, or renal function make that approach appropriate.
Treatment selection depends on the stricture’s anatomy and cause, along with the patient’s symptoms and renal function. Location, length, and severity help define the technical problem, while functional assessment indicates its significance for the kidney. Because these factors vary between patients, no single intervention is suitable for every segmental stricture.