Vertebral Compression Fracture

A vertebral compression fracture is a collapse of one or more vertebral bodies, often caused by weakened bone, trauma, or disease, and can lead to back pain, reduced mobility, and spinal deformity. When the vertebra cannot withstand normal or increased axial loading, its front or entire body may compress, producing a wedge-shaped deformity that can be assessed with clinical examination and imaging. In medicine, recognizing these fractures helps distinguish acute injury from chronic structural change, identify underlying osteoporosis or other pathology, and guide treatment such as analgesia, activity modification, osteoporosis management, and, in selected cases, vertebral augmentation. Early evaluation can reduce complications and inform fracture-prevention strategies.

Vertebral Compression Fracture - Related Videos

Research

JoVE Journal - Bioengineering

Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model

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Cited by 1 •

2017

The goal of this protocol is to generate a nude rat osteoporosis-related vertebral compression fracture model that can be longitudinally evaluated in vivo using a semiautomated microcomputed tomography-based quantitative structural analysis.

Education

JoVE Science Education - Engineering

Compression Tests on Hardened Concrete

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2023

Source: Roberto Leon, Department of Civil and Environmental Engineering, Virginia Tech, Blacksburg, VA There are two distinct stages in a construction project involving concrete. The first stage involves batching, transporting, and casting fresh concrete. At this stage, the material is viscous, and the workability and finishability are the key performance criteria. The second stage occurs when the hydration process begins shortly after the concrete is placed in the form, and the concrete will...

Research

JoVE Journal - Medicine
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Calibrated Forceps Model of Spinal Cord Compression Injury

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Cited by 57 •

2015

Spinal cord injury models should be highly reproducible. We demonstrate that the calibrated forceps compression model of spinal cord injury is an easy to use surgical method for generating reproducible injuries to the murine spinal cord.

Development of a Novel Internal Fixation Model for Rat Radial Fractures: Fracture Healing Assessment and Dorsal Root Ganglion Isolation

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2026

The study innovatively combines sutures and titanium needles for stable internal fixation in a rat radial fracture model. Fracture healing was assessed via micro-computed tomography (micro-CT), and primary dorsal root ganglion (DRG) neurons were isolated and cultured for further investigation.

Research

JoVE Journal - Medicine
Free Sample

A Neonatal Mouse Spinal Cord Compression Injury Model

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Cited by 4 •

2016

This article describes a method for generating a reproducible spinal cord compression injury (SCI) in the neonatal mouse. The model provides an advantageous platform for studying mechanisms of adaptive plasticity that underlie spontaneous functional recovery.

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