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Gecombineerde nabij-infrarood Fluorescent Imaging en Micro-computertomografie voor het direct visualiseren Cerebral Thromboemboli

Article DOI: 10.3791/54294-v • 13:10 min • September 25th, 2016
September 25th, 2016 •
1, 1, 1, 2, 2, 3, 2, 4
1Molecular Imaging and Neurovascular Research Laboratory, Dongguk University College of Medicine, 2Biomedical Research Center, Korea Institute of Science and Technology, 3Research Institute of Advanced Materials, Department of Materials Science and Engineering, Seoul National University, 4Departments of Radiology and Cancer Systems Imaging, University of Texas M.D. Anderson Cancer Center

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Dit protocol beschrijft de toepassing van gecombineerde nabij-infrarood fluorescerende (NIRF) beeldvorming en micro-computertomografie (microCT) voor het visualiseren van cerebrale thromboemboli. Deze techniek maakt de kwantificering van trombus last en evolutie. De NIRF beeldvormende techniek visualiseert fluorescent gelabelde trombus in weggesneden hersenen, terwijl de microCT techniek visualiseert trombus in levende dieren met behulp van goud-nanodeeltjes.

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Geneeskunde computertomografie trombus beeldvorming embolische beroerte microCT goud nanodeeltjes nabij-infrarood fluorescerende beeldvorming moleculaire beeldvorming herseninfarct trombolyse
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