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Journal / Neuroscience / 实验模型研究酸性后处理对脑缺血的神经保护作用…
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Neuroscience

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JoVE Journal Neuroscience
实验模型研究酸性后处理对脑缺血的神经保护作用
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实验模型研究酸性后处理对脑缺血的神经保护作用

Article DOI: 10.3791/55931-v • 10:13 min • July 31st, 2017
July 31st, 2017 •
*1, *1, 1, 1, 1, 1, 1
1Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences, Department of Pharmacology, Key Laboratory of Medical Neurobiology of The Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology, Zhejiang University
* These authors contributed equally

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酸性后处理可防止脑缺血。在这里我们提出两个模型来执行APC。分别通过体外氧葡萄糖剥夺后将皮质硬膜下切片转移到酸性缓冲液中，并在体内大脑中动脉闭塞后吸入20％CO 2 。

Tags

神经生物学，第125期，脑缺血，酸性后处理，皮质激素切片，氧 - 葡萄糖剥夺，大脑中动脉闭塞（MCAO），脑梗死体积，时间窗
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