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En Ex Vivo vævskultur Model for Fibrovascular komplikationer i proliferativ diabetisk retinopati

Article DOI: 10.3791/59090-v • 08:10 min • January 25th, 2019
January 25th, 2019 •
1, 2, 1, 1,3
1Research Programs Unit, Genome-Scale Biology, Biomedicum Helsinki, University of Helsinki, 2Unit of Vitreoretinal Surgery, Ophthalmology, University of Helsinki and Helsinki University Hospital, 3Department of Microbiology, Tumor, and Cell Biology (MTC), Karolinska Institutet

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Vi præsenterer her, en protokol til at studere Patofysiologi af proliferativ diabetisk retinopati ved hjælp af patient-afledte, kirurgisk skåret ud, fibrovascular væv for tre-dimensionelle indfødte karakterisering og ex vivo vævskultur. Dette ex vivo kultur model er også modtagelig for afprøvning eller udvikle nye behandlinger.

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Retraktion spørgsmålet 143 Ex vivo kultur fibrovascular væv proliferativ diabetisk retinopati patient-afledte kliniske prøver Vaskulaturen sygdom Patofysiologi tre-dimensionelle hele-mount immunofluorescens vitrectomy neovessel.
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