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Cancer Research

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Imagem PET/MR não invasiva em um modelo ortotópico de carcinoma hepatocelular em camundongo

Article DOI: 10.3791/63958-v • 07:47 min • August 31st, 2022
August 31st, 2022 •
*1,2, *3, 2, 1, 4, 1,5, 3
1Department of Diagnostic Radiology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, 2Department of Oncology, MRC Oxford Institute for Radiation Oncology, University of Oxford, 3Department of Surgery, School of Clinical Medicine, HKU-SZH & LKS Faculty of Medicine, The University of Hong Kong, 4Department of Biomedical Engineering, The Chinese University of Hong Kong, 5Department of Diagnostic and Interventional Radiology, Kwong Wah Hospital
* These authors contributed equally

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Aqui, apresentamos um protocolo para criar xenoenxertos de carcinoma hepatocelular ortotópico com e sem ligadura da artéria hepática e realizamos tomografia por emissão de pósitrons (PET) não invasiva de hipóxia tumoral usando [18 F]Fluoromisonidazol ([18 F]FMISO) e [18 F]Fluorodesoxiglicose ([18F]FDG).

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Cancer Research Edição 186
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