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Development and Evaluation of a Rat Model of Full-Thickness Cartilage Defects
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Development and Evaluation of a Rat Model of Full-Thickness Cartilage Defects

Article DOI: 10.3791/64475-v • 04:34 min • May 19th, 2023
May 19th, 2023 •
*1, *2, 3, 4, 1, 1, 5, 1, 3, 1, 1
1The First Affiliated Hospital, Zhejiang Chinese Medical University, 2Fuyang Orthopaedics and Traumatology Affiliated Hospital, Zhejiang Chinese Medical University, 3College of Pharmaceutical Science, Zhejiang Chinese Medical University, 4Affiliated Zhejiang Hospital, Zhejiang University School of Medicine, 5Xianju County Hospital of Chinese Medicine
* These authors contributed equally

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Summary
Automatic Translation

This protocol establishes a full-thickness cartilage defects (FTCD) model by drilling holes in the femoral trochlear groove of rats and measuring the subsequent pain behavior and histopathological changes.

Tags

Rat Model Full-thickness Cartilage Defects Evaluation Mimics Clinical FTCD Reliable Animal Model Therapeutic Treatments Easy Technique Growth Observation Clinical Cartilage Defects Pathological Process Therapeutic Drugs Post-traumatic Osteoarthritis Tibia Fibula Femoral Condyle Cochlear Drill Bit Cartilage Surface Anesthetized Rat Operating Table Knee Joint Scalpel Blade Incision Joint Capsule Quadriceps Femoris Tendon
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