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JoVE Journal Cancer Research
Testing av kreftimmunterapi i en humanisert musemodell som bærer menneskelige svulster
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Testing av kreftimmunterapi i en humanisert musemodell som bærer menneskelige svulster

Article DOI: 10.3791/64606-v • 15:24 min • December 16th, 2022
December 16th, 2022 •
*1, *1, 1, 1, 2, 2, 3, 1, 2, 1
1Department of Immunology and Microbiology, School of Medicine, University of Colorado Denver Anschutz Medical Campus, 2Division of Oncology, School of Medicine, University of Colorado Denver Anschutz Medical Campus, 3Department of Medical Oncology, Catalan Institute of Oncology (ICO-L'Hospitalet)
* These authors contributed equally

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Denne protokollen skisserer genereringen av mus av humant immunsystem (HIS) for immunonkologistudier. Instruksjoner og betraktninger i bruken av denne modellen for testing av humane immunterapier på humane svulster implantert i denne modellen presenteres med vekt på å karakterisere responsen av det humane immunsystemet til svulsten.

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