Robotic Tissue Processing

Robotic tissue processing is the automated preparation of biological specimens for microscopic analysis, improving consistency, throughput, and operator safety. Programmable instruments move tissue through controlled fixation, dehydration, clearing, and paraffin infiltration steps, using timed reagent exchanges and regulated conditions to preserve cellular and microbial structures. In immunology and infection research, standardized processing supports tissue sectioning, histological staining, immunohistochemistry, and detection of pathogen-associated changes or immune-cell distribution. By reducing manual variability and enabling parallel sample handling, robotic workflows strengthen comparisons across experiments and help laboratories process clinical or research specimens efficiently.

Robotic Tissue Processing - Related Videos

Research

JoVE Journal - Bioengineering

Rod-based Fabrication of Customizable Soft Robotic Pneumatic Gripper Devices for Delicate Tissue Manipulation

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Cited by 10 •

2016

This protocol describes a rod-based approach, combining 3D-printing and soft lithography techniques for fabricating the soft gripper devices. This approach eliminates the need for an external air source by incorporating a chamber component and reduces the chance of occlusion during the sealing process, particularly for miniaturized pneumatic channels.

Simulation of a Scaled Assembly Process with Collaboration of a Robotic Arm and Monitoring through a Vision System for Quality Control

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Cited by 1 •

2025

Here, we present a protocol for the simulation and monitoring of a scaled semi-automated assembly process, through the collaboration of a collaborative robot and verification via a computer vision system for quality control.

Research

JoVE Journal - Biology
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Robotics and Dynamic Image Analysis for Studies of Gene Expression in Plant Tissues

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Cited by 18 •

2010

We report a method for introduction, tracking and quantitative analysis of GFP expression in plant cells. This method utilizes a custom-designed robotics system for semi-continuous image collection from large numbers of samples, over time. We also demonstrate the use of ImageJ and ImageReady for analysis of image series.

Investigating Motor Skill Learning Processes with a Robotic Manipulandum

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Cited by 2 •

2017

A paradigm is presented for training and analysis of an automated skilled reaching task in rats. Analysis of pulling attempts reveals distinct subprocesses of motor learning.

SSVEP-based Experimental Procedure for Brain-Robot Interaction with Humanoid Robots

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Cited by 12 •

2015

The overall goal of this method is to establish an SSVEP-based experimental procedure by integrating multiple software programs to enable the study of brain-robot interaction with humanoid robots, which is prospective in assisting the sick and elderly as well as performing unsanitary or dangerous jobs.

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