James C. Garmey

Publications

• Liposomal Delivery of PPARα/γ Dual Agonist Tesaglitazar in a Model of Obesity Enriches Macrophage Targeting and Limits Liver and Kidney Drug Effects
  Theranostics. 2020  |   Pubmed ID: 31903139
• Diversification and CXCR4-Dependent Establishment of the Bone Marrow B-1a Cell Pool Governs Atheroprotective IgM Production Linked to Human Coronary Atherosclerosis
  Circulation Research. Oct, 2019  |   Pubmed ID: 31549940
• Protective Role for B-1b B Cells and IgM in Obesity-Associated Inflammation, Glucose Intolerance, and Insulin Resistance
  Arteriosclerosis, Thrombosis, and Vascular Biology. Apr, 2016  |   Pubmed ID: 26868208
• Adipocyte Progenitor Cells Initiate Monocyte Chemoattractant Protein-1-mediated Macrophage Accumulation in Visceral Adipose Tissue
  Molecular Metabolism. Nov, 2015  |   Pubmed ID: 26629403
• Loss of Id3 Increases VCAM-1 Expression, Macrophage Accumulation, and Atherogenesis in Ldlr-/- Mice
  Arteriosclerosis, Thrombosis, and Vascular Biology. Dec, 2012  |   Pubmed ID: 23042815
• B-cell Aortic Homing and Atheroprotection Depend on Id3
  Circulation Research. Jan, 2012  |   Pubmed ID: 22034493
• Increased 12/15-lipoxygenase Enhances Cell Growth, Fibronectin Deposition, and Neointimal Formation in Response to Carotid Injury
  Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2011  |   Pubmed ID: 20947825
• Liver X Receptor Agonists Augment Human Islet Function Through Activation of Anaplerotic Pathways and Glycerolipid/free Fatty Acid Cycling
  The Journal of Biological Chemistry. Feb, 2010  |   Pubmed ID: 20007976
• Peroxisome Proliferator-activated Receptor Gamma Activation Restores Islet Function in Diabetic Mice Through Reduction of Endoplasmic Reticulum Stress and Maintenance of Euchromatin Structure
  Molecular and Cellular Biology. Apr, 2009  |   Pubmed ID: 19237535
• 12-Lipoxygenase-knockout Mice Are Resistant to Inflammatory Effects of Obesity Induced by Western Diet
  American Journal of Physiology. Endocrinology and Metabolism. Nov, 2008  |   Pubmed ID: 18780776
• Research Resource: Nuclear Hormone Receptor Expression in the Endocrine Pancreas
  Molecular Endocrinology (Baltimore, Md.). Oct, 2008  |   Pubmed ID: 18669644
• Pdx1 and BETA2/NeuroD1 Participate in a Transcriptional Complex That Mediates Short-range DNA Looping at the Insulin Gene
  The Journal of Biological Chemistry. Mar, 2008  |   Pubmed ID: 18252719
• Nonobese Diabetic (NOD) Mice Congenic for a Targeted Deletion of 12/15-lipoxygenase Are Protected from Autoimmune Diabetes
  Diabetes. Jan, 2008  |   Pubmed ID: 17940120
• Glucose Regulation of Insulin Gene Transcription and Pre-mRNA Processing in Human Islets
  Diabetes. Mar, 2007  |   Pubmed ID: 17327454
• Role of Chromatin Accessibility in the Occupancy and Transcription of the Insulin Gene by the Pancreatic and Duodenal Homeobox Factor 1
  Molecular Endocrinology (Baltimore, Md.). Dec, 2006  |   Pubmed ID: 16901969
• Combined Treatment with Lisofylline and Exendin-4 Reverses Autoimmune Diabetes
  Biochemical and Biophysical Research Communications. Jun, 2006  |   Pubmed ID: 16643856
• Pdx-1 Links Histone H3-Lys-4 Methylation to RNA Polymerase II Elongation During Activation of Insulin Transcription
  The Journal of Biological Chemistry. Oct, 2005  |   Pubmed ID: 16141209
• Mechanism of Insulin Gene Regulation by the Pancreatic Transcription Factor Pdx-1: Application of Pre-mRNA Analysis and Chromatin Immunoprecipitation to Assess Formation of Functional Transcriptional Complexes
  The Journal of Biological Chemistry. Apr, 2005  |   Pubmed ID: 15743769
• The Transcriptional Repressor Nkx6.1 Also Functions As a Deoxyribonucleic Acid Context-dependent Transcriptional Activator During Pancreatic Beta-cell Differentiation: Evidence for Feedback Activation of the Nkx6.1 Gene by Nkx6.1
  Molecular Endocrinology (Baltimore, Md.). Jun, 2004  |   Pubmed ID: 15056733
• Covalent Histone Modifications Underlie the Developmental Regulation of Insulin Gene Transcription in Pancreatic Beta Cells
  The Journal of Biological Chemistry. Jun, 2003  |   Pubmed ID: 12711597
• Troglitazone, an Insulin-sensitizing Thiazolidinedione, Represses Combined Stimulation by LH and Insulin of De Novo Androgen Biosynthesis by Thecal Cells in Vitro
  The Journal of Clinical Endocrinology and Metabolism. Mar, 2002  |   Pubmed ID: 11889176
• Putative Activation of the Peroxisome Proliferator-activated Receptor Gamma Impairs Androgen and Enhances Progesterone Biosynthesis in Primary Cultures of Porcine Theca Cells
  Biology of Reproduction. Jan, 2002  |   Pubmed ID: 11751282
• Expression of Parathyroid Hormone-related Peptide (PTH-rp) and Its Receptorin the Porcine Ovary: Regulation by Transforming Growth Factor-beta and Possible Paracrine Effects of Granulosa Cell PTH-rp Secretion on Theca Cells
  Biology of Reproduction. Feb, 2000  |   Pubmed ID: 10642570