Jeffrey D. Varner Robert Frederick Smith School of Chemical and Biomolecular Engineering Cornell University Biography Publications Institution JoVE Articles Jeffrey D. Varner has not added a biography. If you are Jeffrey D. Varner and would like to personalize this page please email our Author Liaison for assistance. Publications Improving Designer Glycan Production in Through Model-guided Metabolic Engineering Metabolic Engineering Communications. Dec, 2019 | Pubmed ID: 31008057 Analysis of the Role of Thrombomodulin in All-trans Retinoic Acid Treatment of Coagulation Disorders in Cancer Patients Theoretical Biology & Medical Modelling. 02, 2019 | Pubmed ID: 30764845 Retinoic Acid and 6-formylindolo(3,2-b)carbazole (FICZ) Combination Therapy Reveals Putative Targets for Enhancing Response in Non-APL AML Leukemia & Lymphoma. Jul, 2019 | Pubmed ID: 30570341 Multi-scale Computational Study of the Warburg Effect, Reverse Warburg Effect and Glutamine Addiction in Solid Tumors PLoS Computational Biology. 12, 2018 | Pubmed ID: 30532226 Dynamic Optimization with Particle Swarms (DOPS): a Meta-heuristic for Parameter Estimation in Biochemical Models BMC Systems Biology. 10, 2018 | Pubmed ID: 30314484 Sequence Specific Modeling of E. Coli Cell-Free Protein Synthesis ACS Synthetic Biology. 08, 2018 | Pubmed ID: 29944340 Src Family Kinase Inhibitor Bosutinib Enhances Retinoic Acid-induced Differentiation of HL-60 Leukemia Cells Leukemia & Lymphoma. 12, 2018 | Pubmed ID: 29569971 Potential for Subsets of Wt-NPM1 Primary AML Blasts to Respond to Retinoic Acid Treatment Oncotarget. Jan, 2018 | Pubmed ID: 29423110 Reduced Order Modeling and Analysis of the Human Complement System PloS One. 2017 | Pubmed ID: 29155837 An Effective Model of the Retinoic Acid Induced HL-60 Differentiation Program Scientific Reports. 10, 2017 | Pubmed ID: 29085021 JuPOETs: a Constrained Multiobjective Optimization Approach to Estimate Biochemical Model Ensembles in the Julia Programming Language BMC Systems Biology. 01, 2017 | Pubmed ID: 28122561 Population Heterogeneity in the Epithelial to Mesenchymal Transition Is Controlled by NFAT and Phosphorylated Sp1 PLoS Computational Biology. Dec, 2016 | Pubmed ID: 28027307 Induced Myelomonocytic Differentiation in Leukemia Cells is Accompanied by Noncanonical Transcription Factor Expression FEBS Open Bio. 2015 | Pubmed ID: 26566473 6-Formylindolo(3,2-b)Carbazole (FICZ) Modulates the Signalsome Responsible for RA-Induced Differentiation of HL-60 Myeloblastic Leukemia Cells PloS One. 2015 | Pubmed ID: 26287494 Generating Effective Models and Parameters for RNA Genetic Circuits ACS Synthetic Biology. Aug, 2015 | Pubmed ID: 26046393 GW5074 and PP2 Kinase Inhibitors Implicate Nontraditional C-Raf and Lyn Function As Drivers of Retinoic Acid-induced Maturation Cellular Signalling. Aug, 2015 | Pubmed ID: 25817574 Retinoic Acid Therapy Resistance Progresses from Unilineage to Bilineage in HL-60 Leukemic Blasts PloS One. 2014 | Pubmed ID: 24922062 Ubiquibodies, Synthetic E3 Ubiquitin Ligases Endowed with Unnatural Substrate Specificity for Targeted Protein Silencing The Journal of Biological Chemistry. Mar, 2014 | Pubmed ID: 24474696 Physicochemical Regulation of Endothelial Sprouting in a 3D Microfluidic Angiogenesis Model Journal of Biomedical Materials Research. Part A. Oct, 2013 | Pubmed ID: 23559519 The Src-family Kinase Inhibitor PP2 Rescues Inducible Differentiation Events in Emergent Retinoic Acid-resistant Myeloblastic Leukemia Cells PloS One. 2013 | Pubmed ID: 23554907 Hierarchical Approaches for Systems Modeling in Cardiac Development Wiley Interdisciplinary Reviews. Systems Biology and Medicine. May-Jun, 2013 | Pubmed ID: 23463736 Multiscale Models of Breast Cancer Progression Annals of Biomedical Engineering. Nov, 2012 | Pubmed ID: 23008097 Computational Modeling and Analysis of Insulin Induced Eukaryotic Translation Initiation PLoS Computational Biology. Nov, 2011 | Pubmed ID: 22102801 A Review of the Mammalian Unfolded Protein Response Biotechnology and Bioengineering. Dec, 2011 | Pubmed ID: 21809331 Interferon Regulatory Factor-1 Binds C-Cbl, Enhances Mitogen Activated Protein Kinase Signaling and Promotes Retinoic Acid-induced Differentiation of HL-60 Human Myelo-monoblastic Leukemia Cells Leukemia & Lymphoma. Dec, 2011 | Pubmed ID: 21740303 Modeling and Analysis of Retinoic Acid Induced Differentiation of Uncommitted Precursor Cells Integrative Biology : Quantitative Biosciences from Nano to Macro. May, 2011 | Pubmed ID: 21437295 Ensembles of Uncertain Mathematical Models Can Identify Network Response to Therapeutic Interventions Molecular BioSystems. Nov, 2010 | Pubmed ID: 20844798 Ensembles of Signal Transduction Models Using Pareto Optimal Ensemble Techniques (POETs) Biotechnology Journal. Jul, 2010 | Pubmed ID: 20665647 Arsenic Trioxide Cooperates with All Trans Retinoic Acid to Enhance Mitogen-activated Protein Kinase Activation and Differentiation in PML-RARalpha Negative Human Myeloblastic Leukemia Cells Leukemia & Lymphoma. Sep, 2010 | Pubmed ID: 20615082 Analysis of the Molecular Networks in Androgen Dependent and Independent Prostate Cancer Revealed Fragile and Robust Subsystems PloS One. Jan, 2010 | Pubmed ID: 20126616 Engineering the Spatial Organization of Metabolic Enzymes: Mimicking Nature's Synergy Current Opinion in Biotechnology. Oct, 2008 | Pubmed ID: 18725290 A Test of Highly Optimized Tolerance Reveals Fragile Cell-cycle Mechanisms Are Molecular Targets in Clinical Cancer Trials PloS One. Apr, 2008 | Pubmed ID: 18431497 Computationally Derived Points of Fragility of a Human Cascade Are Consistent with Current Therapeutic Strategies PLoS Computational Biology. Jul, 2007 | Pubmed ID: 17658944 Stochastic Reaction-diffusion Simulation of Enzyme Compartmentalization Reveals Improved Catalytic Efficiency for a Synthetic Metabolic Pathway Metabolic Engineering. Jul, 2007 | Pubmed ID: 17601761 Systems Biology and the Mathematical Modelling of Antibody-directed Enzyme Prodrug Therapy (ADEPT) Systems Biology. Dec, 2005 | Pubmed ID: 16986273 Absolutt kvantifisering av Cell-fri protein syntese metabolisme av reversert-fase flytende kromatografi-Mass massespektrometri Michael Vilkhovoy1, David Dai1, Sandra Vadhin*1, Abhinav Adhikari*1, Jeffrey D. Varner1 1Robert Frederick Smith School of Chemical and Biomolecular Engineering, Cornell University JoVE 60329 생화학
Absolutt kvantifisering av Cell-fri protein syntese metabolisme av reversert-fase flytende kromatografi-Mass massespektrometri Michael Vilkhovoy1, David Dai1, Sandra Vadhin*1, Abhinav Adhikari*1, Jeffrey D. Varner1 1Robert Frederick Smith School of Chemical and Biomolecular Engineering, Cornell University JoVE 60329 생화학