Naoto Hirano Department of Immunology University of Toronto Biography Publications Institution JoVE Articles Naoto Hirano has not added a biography. If you are Naoto Hirano and would like to personalize this page please email our Author Liaison for assistance. Publications BET Bromodomain Inhibition Enhances T Cell Persistence and Function in Adoptive Immunotherapy Models The Journal of Clinical Investigation. Sep, 2016 | Pubmed ID: 27548527 Mouse and Human CD1d-Self-Lipid Complexes Are Recognized Differently by Murine Invariant Natural Killer T Cell Receptors PloS One. 2016 | Pubmed ID: 27213277 CD4(+) and CD8(+) TCRβ Repertoires Possess Different Potentials to Generate Extraordinarily High-avidity T Cells Scientific Reports. Mar, 2016 | Pubmed ID: 27030642 CDR3β Sequence Motifs Regulate Autoreactivity of Human Invariant NKT Cell Receptors Journal of Autoimmunity. Apr, 2016 | Pubmed ID: 26748722 Adoptive T Cell Therapy Targeting CD1 and MR1 Frontiers in Immunology. 2015 | Pubmed ID: 26052329 Optimization of T-cell Reactivity by Exploiting TCR Chain Centricity for the Purpose of Safe and Effective Antitumor TCR Gene Therapy Cancer Immunology Research. Sep, 2015 | Pubmed ID: 25943533 Specific Roles of Each TCR Hemichain in Generating Functional Chain-centric TCR Journal of Immunology (Baltimore, Md. : 1950). Apr, 2015 | Pubmed ID: 25710913 Human Cell-based Artificial Antigen-presenting Cells for Cancer Immunotherapy Immunological Reviews. Jan, 2014 | Pubmed ID: 24329798 使用自体 CD4 T 细胞的 CD8 T 细胞体外扩增的帮助。 PloS One. 2012 | Pubmed ID: 22279573 IL 21 可以在人类的 CD8 + T 细胞中的 STAT 3 依赖方式补充次优荔枝独立 MAPK 激活。 Journal of Immunology (Baltimore, Md. : 1950). Feb, 2012 | Pubmed ID: 22238455 [The Cutting Edge of Antitumor Adoptive Cell Therapy] [Rinsho Ketsueki] The Japanese Journal of Clinical Hematology. Oct, 2011 | Pubmed ID: 21971251 HLA DP4 限制反存活 Th1 和 Th2 响应使用人工抗原递呈细胞的诱导。 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Aug, 2011 | Pubmed ID: 21705450 The Third Consensus Conference on the Treatment of Aplastic Anemia International Journal of Hematology. Jun, 2011 | Pubmed ID: 21617886 建立在人类身上使用体外受 CD8 + T 细胞中的抗肿瘤内存。 Science Translational Medicine. Apr, 2011 | Pubmed ID: 21525398 一个小组的人类细胞为基础的人工 APC 使扩大的长寿抗原特异性 CD4 + T 细胞受到普遍的 HLA 等位基因的限制。 International Immunology. Nov, 2010 | Pubmed ID: 21059769 Juvenile Myelomonocytic Leukemia: Epidemiology, Etiopathogenesis, Diagnosis, and Management Considerations Paediatric Drugs. 2010 | Pubmed ID: 20034338 解离其对立的免疫调节作用的是优化抗肿瘤诱导白细胞介素 21 的 CD8 + T 细胞反应的关键。 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2008 | Pubmed ID: 18829491 Clinical Impact of HLA-DR15, a Minor Population of Paroxysmal Nocturnal Haemoglobinuria-type Cells, and an Aplastic Anaemia-associated Autoantibody in Children with Acquired Aplastic Anaemia British Journal of Haematology. Jul, 2008 | Pubmed ID: 18537977 长寿命抗肿瘤 CD8 + 淋巴细胞养疗法使用人工抗原递呈细胞生成。 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2007 | Pubmed ID: 17363542 Volcanism in Response to Plate Flexure Science (New York, N.Y.). Sep, 2006 | Pubmed ID: 16873612 CD8 + T 细胞抗原表位的免疫原性鉴定来自 γ-珠蛋白,假定的肿瘤相关抗原的少年细胞性白血病。 Blood. Oct, 2006 | Pubmed ID: 16778141 有效演示文稿的自然加工 HLA I 类多肽的研究人工抗原递呈细胞有效的抗肿瘤反应的一代。 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2006 | Pubmed ID: 16707591 参与 CD83 配体诱导长期的扩张的 CD8 + T 细胞和优惠丰富的抗原特异性。 Blood. Feb, 2006 | Pubmed ID: 16239433 The Chemical Structure of the Hawaiian Mantle Plume Nature. Aug, 2005 | Pubmed ID: 16100780 日本再生障碍性贫血患者的抗 Kinectin 和抗 PMS1 抗体的存在。 British Journal of Haematology. Jan, 2005 | Pubmed ID: 15638857 常检测到的再生障碍性贫血患者的自身抗体。 Blood. Dec, 2003 | Pubmed ID: 12947009 共享的肿瘤相关抗原细胞色素 P450 氧化 1B1 已识别特定的细胞毒性 T 细胞。 Blood. Nov, 2003 | Pubmed ID: 12869499 人类的小学和记忆细胞毒 T 淋巴细胞反应被有效地诱导通过 CD40 激活 B 细胞的抗原递呈细胞: 潜在的临床应用。 Blood. May, 2002 | Pubmed ID: 11964299 发电 Tingxi Guo1,2, Toshiki Ochi*2, Munehide Nakatsugawa*2, Yuki Kagoya2, Mark Anczurowski1,2, Chung-Hsi Wang1,2, Muhammed A. Rahman2, Kayoko Saso2, Marcus O. Butler1,2, Naoto Hirano1,2 1Department of Immunology, University of Toronto, 2Princess Margaret Cancer Centre, University Health Network JoVE 54697 면역학 및 감염병학
发电 Tingxi Guo1,2, Toshiki Ochi*2, Munehide Nakatsugawa*2, Yuki Kagoya2, Mark Anczurowski1,2, Chung-Hsi Wang1,2, Muhammed A. Rahman2, Kayoko Saso2, Marcus O. Butler1,2, Naoto Hirano1,2 1Department of Immunology, University of Toronto, 2Princess Margaret Cancer Centre, University Health Network JoVE 54697 면역학 및 감염병학