Roland Malli

Publications

• Intact Mitochondrial Ca(2+) Uniport is Essential for Agonist-induced Activation of Endothelial Nitric Oxide Synthase (eNOS)
  Free Radical Biology & Medicine. Jan, 2017  |   Pubmed ID: 27923677
• Formation of Nitric Oxide by Aldehyde Dehydrogenase-2 Is Necessary and Sufficient for Vascular Bioactivation of Nitroglycerin
  The Journal of Biological Chemistry. Nov, 2016  |   Pubmed ID: 27679490
• PRMT1-mediated Methylation of MICU1 Determines the UCP2/3 Dependency of Mitochondrial Ca(2+) Uptake in Immortalized Cells
  Nature Communications. Sep, 2016  |   Pubmed ID: 27642082
• Resveratrol Specifically Kills Cancer Cells by a Devastating Increase in the Ca2+ Coupling Between the Greatly Tethered Endoplasmic Reticulum and Mitochondria
  Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2016  |   Pubmed ID: 27606689
• Filling a GAP-An Optimized Probe for ER Ca(2+) Imaging In Vivo
  Cell Chemical Biology. Jun, 2016  |   Pubmed ID: 27341431
• Development of Novel FP-based Probes for Live-cell Imaging of Nitric Oxide Dynamics
  Nature Communications. Feb, 2016  |   Pubmed ID: 26842907
• Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (3rd Edition)
  Autophagy. Jan, 2016  |   Pubmed ID: 26799652
• Rearrangement of MICU1 Multimers for Activation of MCU is Solely Controlled by Cytosolic Ca(2.)
  Scientific Reports. Oct, 2015  |   Pubmed ID: 26489515
• UCP2 Modulates Single-channel Properties of a MCU-dependent Ca(2+) Inward Current in Mitochondria
  Pflugers Archiv : European Journal of Physiology. Dec, 2015  |   Pubmed ID: 26275882
• Generation of Red-Shifted Cameleons for Imaging Ca²⁺ Dynamics of the Endoplasmic Reticulum
  Sensors (Basel, Switzerland). Jun, 2015  |   Pubmed ID: 26053751
• Assessment of Mitochondrial Ca²⁺ Uptake
  Methods in Molecular Biology (Clifton, N.J.). 2015  |   Pubmed ID: 25631032
• Oleoyl-lysophosphatidylcholine Limits Endothelial Nitric Oxide Bioavailability by Induction of Reactive Oxygen Species
  PloS One. 2014  |   Pubmed ID: 25419657
• TRPV1 Mediates Cellular Uptake of Anandamide and Thus Promotes Endothelial Cell Proliferation and Network-formation
  Biology Open. Nov, 2014  |   Pubmed ID: 25395667
• Characterization of Rat Serum Amyloid A4 (SAA4): a Novel Member of the SAA Superfamily
  Biochemical and Biophysical Research Communications. Aug, 2014  |   Pubmed ID: 25044109
• IP3-mediated STIM1 Oligomerization Requires Intact Mitochondrial Ca2+ Uptake
  Journal of Cell Science. Jul, 2014  |   Pubmed ID: 24806964
• Adaptations of Energy Metabolism Associated with Increased Levels of Mitochondrial Cholesterol in Niemann-Pick Type C1-deficient Cells
  The Journal of Biological Chemistry. Jun, 2014  |   Pubmed ID: 24790103
• ATP Increases Within the Lumen of the Endoplasmic Reticulum Upon Intracellular Ca2+ Release
  Molecular Biology of the Cell. Feb, 2014  |   Pubmed ID: 24307679
• Mitochondrial Ca(2+) Uniporter (MCU)-dependent and MCU-independent Ca(2+) Channels Coexist in the Inner Mitochondrial Membrane
  Pflugers Archiv : European Journal of Physiology. Jul, 2014  |   Pubmed ID: 24162235
• Molecularly Distinct Routes of Mitochondrial Ca2+ Uptake Are Activated Depending on the Activity of the Sarco/endoplasmic Reticulum Ca2+ ATPase (SERCA)
  The Journal of Biological Chemistry. May, 2013  |   Pubmed ID: 23592775
• N-Arachidonoyl Glycine Suppresses Na⁺/Ca²⁺ Exchanger-mediated Ca²⁺ Entry into Endothelial Cells and Activates BK(Ca) Channels Independently of GPCRs
  British Journal of Pharmacology. Jun, 2013  |   Pubmed ID: 23517055
• Characterization of Distinct Single-channel Properties of Ca²⁺ Inward Currents in Mitochondria
  Pflugers Archiv : European Journal of Physiology. Jul, 2013  |   Pubmed ID: 23397170
• The Endocannabinoid N-arachidonoyl Glycine (NAGly) Inhibits Store-operated Ca2+ Entry by Preventing STIM1-Orai1 Interaction
  Journal of Cell Science. Feb, 2013  |   Pubmed ID: 23239024
• Spatiotemporal Correlations Between Cytosolic and Mitochondrial Ca(2+) Signals Using a Novel Red-Shifted Mitochondrial Targeted Cameleon
  PloS One. 2012  |   Pubmed ID: 23029314
• Mitochondrial Ca2+ Uptake 1 (MICU1) and Mitochondrial Ca2+ Uniporter (MCU) Contribute to Metabolism-secretion Coupling in Clonal Pancreatic β-cells
  The Journal of Biological Chemistry. Oct, 2012  |   Pubmed ID: 22904319
• Acyl Chain-dependent Effect of Lysophosphatidylcholine on Cyclooxygenase (COX)-2 Expression in Endothelial Cells
  Atherosclerosis. Oct, 2012  |   Pubmed ID: 22901457
• The Vascular Barrier-protecting Hawthorn Extract WS® 1442 Raises Endothelial Calcium Levels by Inhibition of SERCA and Activation of the IP3 Pathway
  Journal of Molecular and Cellular Cardiology. Oct, 2012  |   Pubmed ID: 22814436
• Inhibition of Autophagy Rescues Palmitic Acid-induced Necroptosis of Endothelial Cells
  The Journal of Biological Chemistry. Jun, 2012  |   Pubmed ID: 22556413
• Mutation in NSUN2, Which Encodes an RNA Methyltransferase, Causes Autosomal-recessive Intellectual Disability
  American Journal of Human Genetics. May, 2012  |   Pubmed ID: 22541562
• Docosahexaenoic Acid-induced Unfolded Protein Response, Cell Cycle Arrest, and Apoptosis in Vascular Smooth Muscle Cells Are Triggered by Ca²⁺-dependent Induction of Oxidative Stress
  Free Radical Biology & Medicine. May, 2012  |   Pubmed ID: 22391221
• Endothelial Mitochondria--less Respiration, More Integration
  Pflugers Archiv : European Journal of Physiology. Jul, 2012  |   Pubmed ID: 22382745
• Studying Mitochondrial Ca(2+) Uptake - a Revisit
  Molecular and Cellular Endocrinology. Apr, 2012  |   Pubmed ID: 22100614
• Leucine Zipper EF Hand-containing Transmembrane Protein 1 (Letm1) and Uncoupling Proteins 2 and 3 (UCP2/3) Contribute to Two Distinct Mitochondrial Ca2+ Uptake Pathways
  The Journal of Biological Chemistry. Aug, 2011  |   Pubmed ID: 21613221
• The GPR55 Agonist Lysophosphatidylinositol Directly Activates Intermediate-conductance Ca2+ -activated K+ Channels
  Pflugers Archiv : European Journal of Physiology. Aug, 2011  |   Pubmed ID: 21603896
• Sequential Synthesis and Methylation of Phosphatidylethanolamine Promote Lipid Droplet Biosynthesis and Stability in Tissue Culture and in Vivo
  The Journal of Biological Chemistry. May, 2011  |   Pubmed ID: 21454708
• Triacylglycerol Accumulation Activates the Mitochondrial Apoptosis Pathway in Macrophages
  The Journal of Biological Chemistry. Mar, 2011  |   Pubmed ID: 21196579
• Uncoupling Protein 3 Adjusts Mitochondrial Ca(2+) Uptake to High and Low Ca(2+) Signals
  Cell Calcium. Nov, 2010  |   Pubmed ID: 21047682
• GPR55-dependent and -independent Ion Signalling in Response to Lysophosphatidylinositol in Endothelial Cells
  British Journal of Pharmacology. Sep, 2010  |   Pubmed ID: 20735417
• Acyl Chain-dependent Effect of Lysophosphatidylcholine on Endothelial Prostacyclin Production
  Journal of Lipid Research. Oct, 2010  |   Pubmed ID: 20610733
• Mitochondrial Ca2+ Uptake and Not Mitochondrial Motility is Required for STIM1-Orai1-dependent Store-operated Ca2+ Entry
  Journal of Cell Science. Aug, 2010  |   Pubmed ID: 20587595
• The Contribution of UCP2 and UCP3 to Mitochondrial Ca(2+) Uptake is Differentially Determined by the Source of Supplied Ca(2+)
  Cell Calcium. May, 2010  |   Pubmed ID: 20403634
• Vesicular Calcium Regulates Coat Retention, Fusogenicity, and Size of Pre-Golgi Intermediates
  Molecular Biology of the Cell. Mar, 2010  |   Pubmed ID: 20089833
• Mitochondrial Ca2+ Channels: Great Unknowns with Important Functions
  FEBS Letters. May, 2010  |   Pubmed ID: 20074570
• Lysophosphatidic Acid Receptor Activation Affects the C13NJ Microglia Cell Line Proteome Leading to Alterations in Glycolysis, Motility, and Cytoskeletal Architecture
  Proteomics. Jan, 2010  |   Pubmed ID: 19899077
• Mitochondrial Protein Phosphorylation: Instigator or Target of Lipotoxicity?
  Trends in Endocrinology and Metabolism: TEM. May, 2009  |   Pubmed ID: 19356948
• Cytosolic Ca2+ Prevents the Subplasmalemmal Clustering of STIM1: an Intrinsic Mechanism to Avoid Ca2+ Overload
  Journal of Cell Science. Oct, 2008  |   Pubmed ID: 18765567
• Integrin Clustering Enables Anandamide-induced Ca2+ Signaling in Endothelial Cells Via GPR55 by Protection Against CB1-receptor-triggered Repression
  Journal of Cell Science. May, 2008  |   Pubmed ID: 18445684
• The C-terminal Region of Human Adipose Triglyceride Lipase Affects Enzyme Activity and Lipid Droplet Binding
  The Journal of Biological Chemistry. Jun, 2008  |   Pubmed ID: 18445597
• Mitochondrial Ca2+, the Secret Behind the Function of Uncoupling Proteins 2 and 3?
  Cell Calcium. Jul, 2008  |   Pubmed ID: 18282596
• Mitochondria and Ca(2+) Signaling: Old Guests, New Functions
  Pflugers Archiv : European Journal of Physiology. Dec, 2007  |   Pubmed ID: 17611770
• Uncoupling Proteins 2 and 3 Are Fundamental for Mitochondrial Ca2+ Uniport
  Nature Cell Biology. Apr, 2007  |   Pubmed ID: 17351641
• Mg2+ Deprivation Elicits Rapid Ca2+ Uptake and Activates Ca2+/calcineurin Signaling in Saccharomyces Cerevisiae
  Eukaryotic Cell. Apr, 2007  |   Pubmed ID: 17337637
• Mitochondria Maintain Maturation and Secretion of Lipoprotein Lipase in the Endoplasmic Reticulum
  The Biochemical Journal. May, 2006  |   Pubmed ID: 16466345
• A New Type of Non-Ca2+-buffering Apo(a)-based Fluorescent Indicator for Intraluminal Ca2+ in the Endoplasmic Reticulum
  The Journal of Biological Chemistry. Feb, 2006  |   Pubmed ID: 16368693
• Twenty Years of Calcium Imaging: Cell Physiology to Dye For
  Molecular Interventions. Apr, 2005  |   Pubmed ID: 15821159
• Hyperglycemic Conditions Affect Shape and Ca2+ Homeostasis of Mitochondria in Endothelial Cells
  Journal of Cardiovascular Pharmacology. Oct, 2004  |   Pubmed ID: 15454850
• Kisspeptin-10, a KiSS-1/metastin-derived Decapeptide, is a Physiological Invasion Inhibitor of Primary Human Trophoblasts
  Journal of Cell Science. Mar, 2004  |   Pubmed ID: 15020672
• Heterozygous Missense Mutations in BSCL2 Are Associated with Distal Hereditary Motor Neuropathy and Silver Syndrome
  Nature Genetics. Mar, 2004  |   Pubmed ID: 14981520
• Anandamide Initiates Ca(2+) Signaling Via CB2 Receptor Linked to Phospholipase C in Calf Pulmonary Endothelial Cells
  British Journal of Pharmacology. Dec, 2003  |   Pubmed ID: 14645143
• Sustained Ca2+ Transfer Across Mitochondria is Essential for Mitochondrial Ca2+ Buffering, Sore-operated Ca2+ Entry, and Ca2+ Store Refilling
  The Journal of Biological Chemistry. Nov, 2003  |   Pubmed ID: 12941956
• Mitochondria Efficiently Buffer Subplasmalemmal Ca2+ Elevation During Agonist Stimulation
  The Journal of Biological Chemistry. Mar, 2003  |   Pubmed ID: 12529366
• Novel High Energy Intermediate Analogues with Triazasterol-related Structures As Inhibitors of Ergosterol Biosynthesis. Part I: Synthesis and Antifungal Activity of N-alkyl-N'-(phenethyl- and Cyclohexenylethyl)guanidines and N2-substituted 2-imidazolinamines
  Archiv Der Pharmazie. 2002  |   Pubmed ID: 12596218
• Nitric Oxide Inhibits Capacitative Ca2+ Entry by Suppression of Mitochondrial Ca2+ Handling
  British Journal of Pharmacology. Nov, 2002  |   Pubmed ID: 12411413
• Functional Analysis of Histamine Receptor Subtypes Involved in Endothelium-mediated Relaxation of the Human Uterine Artery
  Clinical and Experimental Pharmacology & Physiology. Aug, 2002  |   Pubmed ID: 12100006
• Subplasmalemmal Endoplasmic Reticulum Controls K(Ca) Channel Activity Upon Stimulation with a Moderate Histamine Concentration in a Human Umbilical Vein Endothelial Cell Line
  The Journal of Physiology. Apr, 2002  |   Pubmed ID: 11927670
• Tissue-specific Expression of Human Lipoprotein Lipase in the Vascular System Affects Vascular Reactivity in Transgenic Mice
  British Journal of Pharmacology. Jan, 2002  |   Pubmed ID: 11786490
• Oxidized Phospholipids Stimulate Tissue Factor Expression in Human Endothelial Cells Via Activation of ERK/EGR-1 and Ca(++)/NFAT
  Blood. Jan, 2002  |   Pubmed ID: 11756172