Uwe-Karsten Hanisch Institute of Neuropathology University of Göttingen Biography Publications Institution JoVE Articles Uwe-Karsten Hanisch has not added a biography. If you are Uwe-Karsten Hanisch and would like to personalize this page please email our Author Liaison for assistance. Publications Zoledronic Acid Inhibits Macrophage/microglia-assisted Breast Cancer Cell Invasion Oncotarget. Aug, 2013 | Pubmed ID: 24036536 Toll-like Receptor 2 Mediates Microglia/brain Macrophage MT1-MMP Expression and Glioma Expansion Neuro-oncology. Oct, 2013 | Pubmed ID: 24014382 Empty Liposomes Induce Antitumoral Effects Associated with Macrophage Responses Distinct from Those of the TLR1/2 Agonist Pam3CSK 4 (BLP) Cancer Immunology, Immunotherapy : CII. Oct, 2013 | Pubmed ID: 23917775 Carcinoma Cells Misuse the Host Tissue Damage Response to Invade the Brain Glia. Aug, 2013 | Pubmed ID: 23832647 Functional Diversity of Microglia - How Heterogeneous Are They to Begin With? Frontiers in Cellular Neuroscience. 2013 | Pubmed ID: 23717262 Histone Deacetylase Inhibitors Suppress Immune Activation in Primary Mouse Microglia Journal of Neuroscience Research. Sep, 2013 | Pubmed ID: 23686642 Resistance of the Brain to Escherichia Coli K1 Infection Depends on MyD88 Signaling and the Contribution of Neutrophils and Monocytes Infection and Immunity. May, 2013 | Pubmed ID: 23478323 Proteins in Microglial Activation--inputs and Outputs by Subsets Current Protein & Peptide Science. Feb, 2013 | Pubmed ID: 23441901 Influence of Methylene Blue on Microglia-induced Inflammation and Motor Neuron Degeneration in the SOD1(G93A) Model for ALS PloS One. 2012 | Pubmed ID: 22952827 Toll-like Receptor Activation Reveals Developmental Reorganization and Unmasks Responder Subsets of Microglia Glia. Dec, 2012 | Pubmed ID: 22911652 The Nucleotide-binding Oligomerization Domain-containing-2 Ligand Muramyl Dipeptide Enhances Phagocytosis and Intracellular Killing of Escherichia Coli K1 by Toll-like Receptor Agonists in Microglial Cells Journal of Neuroimmunology. Nov, 2012 | Pubmed ID: 22889567 Complement Receptor-3 Negatively Regulates the Phagocytosis of Degenerated Myelin Through Tyrosine Kinase Syk and Cofilin Journal of Neuroinflammation. 2012 | Pubmed ID: 22776089 Reduced Astrocytic NF-κB Activation by Laquinimod Protects from Cuprizone-induced Demyelination Acta Neuropathologica. Sep, 2012 | Pubmed ID: 22766690 Expression of Coagulation Factors and Their Receptors in Tumor Tissue and Coagulation Factor Upregulation in Peripheral Blood of Patients with Cerebral Carcinoma Metastases Journal of Cancer Research and Clinical Oncology. Jan, 2012 | Pubmed ID: 22065054 Physiology of Microglia Physiological Reviews. Apr, 2011 | Pubmed ID: 21527731 Selective Transfer of Exosomes from Oligodendrocytes to Microglia by Macropinocytosis Journal of Cell Science. Feb, 2011 | Pubmed ID: 21242314 CD14 and TRIF Govern Distinct Responsiveness and Responses in Mouse Microglial TLR4 Challenges by Structural Variants of LPS Brain, Behavior, and Immunity. Jul, 2011 | Pubmed ID: 20951794 Inflammatory Cytokine Release of Astrocytes in Vitro is Reduced by All-trans Retinoic Acid Journal of Neuroimmunology. Dec, 2010 | Pubmed ID: 20826012 The Viral TLR3 Agonist Poly(I:C) Stimulates Phagocytosis and Intracellular Killing of Escherichia Coli by Microglial Cells Neuroscience Letters. Sep, 2010 | Pubmed ID: 20599470 Inflammatory Chemokine Release of Astrocytes in Vitro is Reduced by All-trans Retinoic Acid Journal of Neurochemistry. Sep, 2010 | Pubmed ID: 20557428 Microglia Promote Colonization of Brain Tissue by Breast Cancer Cells in a Wnt-dependent Way Glia. Sep, 2010 | Pubmed ID: 20549749 T Cell-dependence of Lassa Fever Pathogenesis PLoS Pathogens. Mar, 2010 | Pubmed ID: 20360949 Locus Ceruleus Controls Alzheimer's Disease Pathology by Modulating Microglial Functions Through Norepinephrine Proceedings of the National Academy of Sciences of the United States of America. Mar, 2010 | Pubmed ID: 20231476 TRPM3 is Expressed in Sphingosine-responsive Myelinating Oligodendrocytes Journal of Neurochemistry. Aug, 2010 | Pubmed ID: 20163522 Toll-like Receptor Stimulation Enhances Phagocytosis and Intracellular Killing of Nonencapsulated and Encapsulated Streptococcus Pneumoniae by Murine Microglia Infection and Immunity. Feb, 2010 | Pubmed ID: 19933834 Fibronectin Stimulates Escherichia Coli Phagocytosis by Microglial Cells Glia. Feb, 2010 | Pubmed ID: 19780198 Therapeutic and Adverse Effects of a Non-steroidal Glucocorticoid Receptor Ligand in a Mouse Model of Multiple Sclerosis PloS One. 2009 | Pubmed ID: 19997594 FK506 Protects Against Various Immune Responses and Secondary Degeneration Following Cerebral Ischemia Anatomical Record (Hoboken, N.J. : 2007). Dec, 2009 | Pubmed ID: 19728359 Toll-like Receptor Prestimulation Increases Phagocytosis of Escherichia Coli DH5alpha and Escherichia Coli K1 Strains by Murine Microglial Cells Infection and Immunity. Jan, 2009 | Pubmed ID: 18981243 Thrombin-induced Regulation of CD95(Fas) Expression in the N9 Microglial Cell Line: Evidence for Involvement of Proteinase-activated Receptor(1) and Extracellular Signal-regulated Kinase 1/2 Neurochemical Research. Mar, 2009 | Pubmed ID: 18686031 Inhibition of Rho-dependent Pathways by Clostridium Botulinum C3 Protein Induces a Proinflammatory Profile in Microglia Glia. Aug, 2008 | Pubmed ID: 18442097 Distinct and Nonredundant in Vivo Functions of IFNAR on Myeloid Cells Limit Autoimmunity in the Central Nervous System Immunity. May, 2008 | Pubmed ID: 18424188 Thrombin Regulates CD40 Expression in Microglial Cells Neuroreport. May, 2008 | Pubmed ID: 18418252 Toll-like Receptors: Roles in Neuroprotection? Trends in Neurosciences. Apr, 2008 | Pubmed ID: 18329736 Myelin-phagocytosing Macrophages in Isolated Sciatic and Optic Nerves Reveal a Unique Reactive Phenotype Glia. Feb, 2008 | Pubmed ID: 18069669 Lipopolysaccharide is a Frequent and Significant Contaminant in Microglia-activating Factors Glia. Jan, 2008 | Pubmed ID: 17910052 Microglia in the Adult Brain Arise from Ly-6ChiCCR2+ Monocytes Only Under Defined Host Conditions Nature Neuroscience. Dec, 2007 | Pubmed ID: 18026096 Microglia: Active Sensor and Versatile Effector Cells in the Normal and Pathologic Brain Nature Neuroscience. Nov, 2007 | Pubmed ID: 17965659 Fibronectin is Elevated in the Cerebrospinal Fluid of Patients Suffering from Bacterial Meningitis and Enhances Inflammation Caused by Bacterial Products in Primary Mouse Microglial Cell Cultures Journal of Neurochemistry. Sep, 2007 | Pubmed ID: 17561936 A Paediatric Supratentorial Primitive Neuroectodermal Tumour Associated with Malignant Astrocytic Transformation and a Clonal Origin of Both Components Neurosurgical Review. Apr, 2007 | Pubmed ID: 17333087 Activation of Microglial Cells by Thrombin: Past, Present, and Future Seminars in Thrombosis and Hemostasis. Apr, 2006 | Pubmed ID: 16673268 Microglial Phenotype: is the Commitment Reversible? Trends in Neurosciences. Feb, 2006 | Pubmed ID: 16406093 Unraveling Thrombin's True Microglia-activating Potential: Markedly Disparate Profiles of Pharmaceutical-grade and Commercial-grade Thrombin Preparations Journal of Neurochemistry. Nov, 2005 | Pubmed ID: 16271051 C-Jun N-terminal Kinases (JNKs) Mediate Pro-inflammatory Actions of Microglia Glia. May, 2005 | Pubmed ID: 15739188 Microglia Metabolic Brain Disease. Dec, 2004 | Pubmed ID: 15554430 The Microglia-activating Potential of Thrombin: the Protease is Not Involved in the Induction of Proinflammatory Cytokines and Chemokines The Journal of Biological Chemistry. Dec, 2004 | Pubmed ID: 15452111 The Tyrosine Kinase Inhibitor AG126 Restores Receptor Signaling and Blocks Release Functions in Activated Microglia (brain Macrophages) by Preventing a Chronic Rise in the Intracellular Calcium Level Journal of Neurochemistry. Aug, 2004 | Pubmed ID: 15255929 Tyrosine Kinase Inhibition Reduces Inflammation in the Acute Stage of Experimental Pneumococcal Meningitis Infection and Immunity. Jun, 2004 | Pubmed ID: 15155632 Expression of Proteinase-activated Receptors in Mouse Microglial Cells Neuroreport. Dec, 2003 | Pubmed ID: 14663194 Purinergic Receptors on Microglial Cells: Functional Expression in Acute Brain Slices and Modulation of Microglial Activation in Vitro The European Journal of Neuroscience. Jun, 2003 | Pubmed ID: 12814360 Elevation of Basal Intracellular Calcium As a Central Element in the Activation of Brain Macrophages (microglia): Suppression of Receptor-evoked Calcium Signaling and Control of Release Function The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2003 | Pubmed ID: 12805281 Interferon-gamma Differentially Modulates the Release of Cytokines and Chemokines in Lipopolysaccharide- and Pneumococcal Cell Wall-stimulated Mouse Microglia and Macrophages The European Journal of Neuroscience. Dec, 2002 | Pubmed ID: 12473079 Microglia As a Source and Target of Cytokines Glia. Nov, 2002 | Pubmed ID: 12379902 एक Organotypic मस्तिष्क टुकड़ा और कार्सिनोमा कोशिकाओं के 3 डी उपगोल साथ coculture प्रणाली Han-Ning Chuang1, Raphaela Lohaus1, Uwe-Karsten Hanisch2, Claudia Binder1, Faramarz Dehghani*3, Tobias Pukrop*1 1Department of Hematology and Oncology, University of Göttingen, 2Institute of Neuropathology, University of Göttingen, 3Institute of Anatomy and Cellbiology, University of Halle JoVE 50881 의학
एक Organotypic मस्तिष्क टुकड़ा और कार्सिनोमा कोशिकाओं के 3 डी उपगोल साथ coculture प्रणाली Han-Ning Chuang1, Raphaela Lohaus1, Uwe-Karsten Hanisch2, Claudia Binder1, Faramarz Dehghani*3, Tobias Pukrop*1 1Department of Hematology and Oncology, University of Göttingen, 2Institute of Neuropathology, University of Göttingen, 3Institute of Anatomy and Cellbiology, University of Halle JoVE 50881 의학
