Internal Cannula
Internal Cannula - Related Videos
04:01
Cannula Implantation into the Cisterna Magna in a Mouse Model
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2025
Source: Xavier, A. L. R., et al. Cannula Implantation into the Cisterna Magna of Rodents. J. Vis. Exp. (2018)This video demonstrates the procedure for implanting a cannula into the cisterna magna of an anesthetized mouse. The technique involves guiding a needle-mounted cannula through the dura into the inverted triangular cisterna magna and securing it for targeted delivery into the cerebrospinal fluid.
01:29
Administering Oxygen by Nasal Cannula
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2025
Oxygen therapy is critical to patient care, especially for those struggling with respiratory issues. This intervention increases the oxygen concentration in the lungs, enhancing the amount of oxygen transported to the body's tissues. One standard method of delivering supplemental oxygen is through a nasal cannula, a non-invasive device that provides low to medium oxygen concentrations. Nasal Cannulas A nasal cannula is a lightweight tube split into two prongs placed in the nostrils, connected...
09:18
Internal Standards
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2023
Source: Laboratory of Dr. B. Jill Venton - University of Virginia The goal of many chemical analyses is a quantitative analysis, where the amount of a substance in a sample is determined. In order to accurately calculate the concentration of an unknown from a sample, careful sample preparation is key. Every time a sample is handled or transferred, some of the sample can be lost. There are strategies however, for minimizing sample loss. There are also strategies for coping with sample loss and...
02:00
Internal Energy
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2020
The total of all possible kinds of energy present in a substance is called the internal energy (U), sometimes symbolized as E. Suppose a system with initial internal energy, Uinitial, undergoes a change in energy (transfer of work or heat), and the final internal energy of the system is Ufinal. Change in internal energy equals the difference between Ufinal and Uinitial. Although the values for Ufinal and Uinitial cannot be determined for a system, the first law of thermodynamics only...
02:24
Tracheal Cannulation in Rabbit Model: A Procedure to Insert Tracheal Cannula into the Rabbit Trachea
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2025
This video demonstrates the surgical creation of an opening in the rabbit trachea to insert a tracheal cannula for artificially ventilating the lungs.
FAQs
Its stable placement allows investigators to access the same physiological site repeatedly across a study. This supports timed interventions and serial fluid collection without requiring a new surgical disruption for every measurement. In longitudinal experiments, the approach helps relate changes in local inflammation, pathogen spread, or treatment response to the timing of each intervention.
The target tissue, internal compartment, and intended route determine how the cannula can be used and what information it can provide. A route selected for local delivery may support analysis of responses at that site, whereas another route may be more suitable for monitoring or collecting fluids. Study conditions therefore shape both access and interpretation.
After the device has been positioned and secured, researchers can perform multiple interventions through the established passage. This reduces the need for additional surgical disruption during later time points, helping separate responses associated with the experimental treatment from changes caused by repeated access procedures. The benefit is especially relevant when tracking inflammation or infection over time.
The workflow begins with placement at the selected physiological site, followed by securing the cannula and establishing its external connection. Investigators can then use the access for controlled delivery, fluid collection, or monitoring according to the experimental route and study conditions. Repeated use requires maintaining the intended connection between the internal compartment and the external system.
They are useful when a study requires timed administration of infectious agents, serial sampling, or observation of pathogen spread over multiple time points. The controlled access can connect intervention timing with subsequent local host responses. This makes the approach relevant for examining how infection develops and how treatment effects change during the course of an experiment.
Internal cannula access can support analysis of local inflammatory responses after immune-active compounds or infectious agents are administered. Repeated sampling also enables investigators to examine physiological changes over time rather than relying only on a single endpoint. These measurements can help compare response patterns under different study conditions and evaluate changes associated with treatment.