Cbf Atlas
Cbf Atlas - Related Videos
03:38
Developing a Cerebral Blood Flow Atlas for Blood Flow Mapping
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2025
Source: Tan, Z., et al., Construction and Application of Cerebral Functional Region-Based Cerebral Blood Flow Atlas Using Magnetic Resonance Imaging-Arterial Spin Labeling. J. Vis. Exp. (2024).This video demonstrates the method to construct a cerebral blood flow atlas by integrating magnetic resonance imaging or MRI-arterial spin labeling data with segmented brain regions, visualizing blood flow patterns, and quantifying flow levels across functional areas.
09:08
Production of Tissue Microarrays, Immunohistochemistry Staining and Digitalization Within the Human Protein Atlas
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Cited by 202 •
2012
Tissue microarrays allows for an efficient method to gain concurrent information from a multitude of tissues. Representative parts of tissues are assembled into a single paraffin block. Sections from the block are used for immunohistochemistry and analysis of protein expression patterns. Digital scanning generates corresponding images for distribution of data.
09:29
Stereotactic Atlas-Guided Laser Capture Microdissection of Brain Regions Affected by Traumatic Injury
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Cited by 3 •
2017
We describe the use of laser capture microdissection to obtain samples of distinct cell populations from different brain regions for gene and microRNA analysis. This technique allows the study of differential effects of traumatic brain injury in specific regions of the rat brain.
05:23
Construction and Application of Cerebral Functional Region-Based Cerebral Blood Flow Atlas Using Magnetic Resonance Imaging-Arterial Spin Labeling
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2024
This study integrated magnetic resonance imaging- arterial spin labeling images to derive cerebral blood flow (CBF) atlas for cerebral functional regions. Comparing typical healthy and chronic cerebral ischemia CBF atlases revealed significant differences in regional CBF distributions, enabling rapid, noninvasive assessments of functional CBF to assist in diagnosis and evaluate therapeutics.
16:23
Fiber Connections of the Supplementary Motor Area Revisited: Methodology of Fiber Dissection, DTI, and Three Dimensional Documentation
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Cited by 32 •
2017
The purpose of this study is to show each step of the fiber dissection technique on human cadaveric brains, the 3D documentation of these dissections, and the diffusion tensor imaging of the anatomically dissected fiber pathways.
FAQs
Standardization is the key mechanism. A CBF Atlas places cerebral blood flow measurements within a common anatomical framework, allowing a value from one brain region to be compared with values from other regions, individuals, or patient groups. This organization turns regional perfusion data into a structured reference for recognizing departures from expected spatial patterns and supporting quantitative interpretation.
Anatomical standardization gives measurements a shared spatial context. Without that context, a regional value cannot be interpreted as readily against corresponding regions in another individual or patient group. Within a CBF Atlas, spatially organized measurements support comparisons across brain regions and populations, making it easier to identify abnormal perfusion patterns rather than viewing values in isolation.
Arterial spin labeling is one perfusion-imaging approach that can provide the cerebral blood flow measurements used in an atlas. Its role is therefore upstream of interpretation: imaging generates regional measurements, while the atlas integrates those data into standardized anatomy. This separation lets users focus on spatial patterns and comparisons without treating the reference map as a substitute for imaging.
First, cerebral blood flow is measured with perfusion imaging such as arterial spin labeling. Those measurements are then related to the atlas’s standardized anatomical framework, where regional values can be examined against other brain regions, individuals, or patient groups. The resulting comparison helps clinicians or researchers assess whether the observed distribution suggests abnormal perfusion.
Use is most relevant when the goal is to assess cerebrovascular function or interpret regional perfusion in neurological and psychiatric disorders. The atlas supplies a consistent reference for examining spatial patterns and interpreting quantitative imaging findings. It can therefore support disease characterization and help clinicians or researchers organize regional blood-flow information for medical or scientific analysis.
Comparisons can reveal abnormal perfusion patterns and help characterize disease-related differences in cerebral blood flow. The same framework also supports treatment evaluation by organizing perfusion measurements in a consistent spatial context. Consequently, a CBF Atlas can connect quantitative imaging results with assessments of disease features and therapeutic effects without separating those findings from their anatomical location.
Because it links cerebral blood flow values to specific brain regions and enables comparison across individuals or patient groups, a CBF Atlas provides a basis for quantitative features that describe an individual’s perfusion pattern. Those spatially organized features can contribute to personalized brain biomarkers while retaining the anatomical context needed to relate measurements to cerebrovascular or disease-related findings.