Nerve Transfer Rehabilitation

Nerve transfer rehabilitation is the structured process of restoring movement and function after a healthy donor nerve is surgically connected to a damaged target nerve. Recovery depends on axonal regrowth across the nerve junction, followed by reinnervation of muscles and gradual retraining of the brain to control the transferred nerve’s new function. Rehabilitation combines protected healing, progressive strengthening, sensory and motor re-education, and task-specific practice, with timing adjusted to nerve regeneration and clinical recovery. In medicine, this approach supports functional recovery after traumatic peripheral nerve injuries and helps clinicians assess reinnervation, prevent secondary weakness, and optimize long-term independence.

Nerve Transfer Rehabilitation - Related Videos

Research

JoVE Journal - Medicine
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Structured Motor Rehabilitation After Selective Nerve Transfers

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Cited by 20 •

2019

Here, we present a protocol for the motor rehabilitation of patients with severe nerve injuries and selective nerve transfer surgery. It aims at restoring the motor function proposing several stages in patient education, early-stage therapy after surgery and interventions for rehabilitation after successful re-innervation of the nerve’s target.

Research

JoVE EoE - Neurotherapeutics

Gene Transfer into Schwann Cells of the Rodent Sciatic Nerve via Electroporation

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2025

Source: Ino, D. et. al., In Vivo Gene Transfer to Schwann Cells in the Rodent Sciatic Nerve by Electroporation. J. Vis. Exp. (2016)This video demonstrates in vivo gene transfer to Schwann cells of the rodent sciatic nerve using electroporation. A plasmid DNA–dye solution is injected into the nerve, and electric pulses facilitate DNA entry. The DNA later integrates into the cell’s genome, enabling successful gene transfer in Schwann cells.

Research

JoVE Journal - Neuroscience
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In Vivo Gene Transfer to Schwann Cells in the Rodent Sciatic Nerve by Electroporation

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Cited by 4 •

2016

Here, we present an in vivo technique for gene transfer to Schwann cells (SCs) in the rodent sciatic nerve. This simple technique is useful for investigating signaling mechanisms involved in the development and maintenance of myelinating SCs.

Mobile Game-based Virtual Reality Program for Upper Extremity Stroke Rehabilitation

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Cited by 102 •

2018

Here, we present a protocol to develop and apply a mobile game-based virtual reality program for the recovery of upper limb dysfunction in patients with stroke. The present study shows that the mobile program is feasible and effectively promotes upper limb recovery in stroke patients.

Haptic/Graphic Rehabilitation: Integrating a Robot into a Virtual Environment Library and Applying it to Stroke Therapy

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Cited by 8 •

2011

Recently, a vast amount of prospects have come available for human-robot interactive systems. In this paper we outline the integration of a new robotic device with open source software that can rapidly make possible a library of interactive functionality. We then outline a clinical application for a neurorehabilitation application.

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