Mobility Measurement
Mobility Measurement - Related Videos
06:57
Electrophoretic Mobility Shift Assay (EMSA)
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2023
The electrophoretic mobility shift assay (EMSA) is a biochemical procedure used to elucidate binding between proteins and nucleic acids. In this assay a radiolabeled nucleic acid and test protein are mixed. Binding is determined via gel electrophoresis which separates components based on mass, charge, and conformation. This video shows the concepts of EMSA and a general procedure, including gel and protein preparation, binding, electrophoresis, and detection. Applications covered in this video...
08:54
Development of a Mobile Mitochondrial Physiology Laboratory for Measuring Mitochondrial Energetics in the Field
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Cited by 2 •
2021
We designed and constructed a mobile laboratory to measure respiration rates in isolated mitochondria of wild animals captured at field locations. Here, we describe the design and outfitting of a mobile mitochondrial laboratory and the associated laboratory protocols.
01:26
Mobile Marketing
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2024
As consumers increasingly rely on smartphones and other mobile devices for browsing, communication, and shopping, mobile marketing has become essential in today's digital world. Brands must adjust their strategies to engage users where they spend most of their time, which is on mobile screens. Understanding mobile user behavior is crucial for successful mobile marketing. Mobile users typically interact with their devices briefly and frequently throughout the day. They prefer content that is...
08:40
Using a Cyclic Ion Mobility Spectrometer for Tandem Ion Mobility Experiments
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Cited by 2 •
2022
Ion mobility spectrometry (IMS) is an interesting complement to mass spectrometry for the characterization of biomolecules, notably because it is sensitive to isomerism. This protocol describes a tandem IMS (IMS/IMS) experiment, which allows the isolation of a molecule and the generation of the mobility profiles of its fragments.
11:49
Characterization of G Protein-coupled Receptors by a Fluorescence-based Calcium Mobilization Assay
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Cited by 26 •
2014
The here described fluorescence-based calcium mobilization assay is a medium-throughput reverse pharmacology screening system for the identification of functionally activating ligand(s) of orphan G protein-coupled receptors (GPCRs).
FAQs
Gait speed, distance traveled, posture, balance, and limb trajectories provide complementary views of movement. Speed and distance can indicate overall performance, while posture, balance, and limb paths expose coordination and control patterns that may change with altered strength or sensory processing. Examining several variables together helps distinguish broad mobility changes from specific motor deficits.
These approaches convert movement into quantitative data through different measurement formats. Video tracking can follow visible movement across a task, motion sensors can record movement-related signals, and instrumented walkways can support measurements during walking. The appropriate choice depends on which variables, such as gait speed, balance, or limb trajectories, are needed for the experimental question.
Standardized tasks make movement outcomes more comparable across individuals, experimental conditions, and stages of recovery. Keeping the task context consistent helps researchers interpret whether differences in speed, posture, balance, or limb movement reflect a biological change rather than a change in testing conditions. This consistency is especially important in longitudinal studies and rehabilitation research.
The measurements provide related but distinct indicators of motor performance. Distance traveled or gait speed may show an overall reduction in mobility, whereas posture, balance, and limb trajectories can reveal altered coordination or motor control. Interpreting these variables together allows researchers to identify patterns associated with strength, sensory processing, or coordination rather than relying on a single movement outcome.
A typical workflow begins by selecting a standardized movement task and deciding which outcomes are relevant, such as gait speed, distance, posture, balance, or limb trajectories. Researchers then record movement with video tracking, motion sensors, or an instrumented walkway and compare the resulting data across participants, conditions, or recovery stages to identify meaningful changes.
Mobility measurement is useful when researchers need objective evidence of motor changes in neurological disorders, injury, aging, or rehabilitation. Quantified movement supports studies of neural circuits and helps track performance across recovery stages. In rehabilitation contexts, repeated measurements can show whether mobility-related outcomes change over time under different conditions or following intervention.