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Udskæring og dyrkning af grisehjerter under fysiologiske forhold
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Udskæring og dyrkning af grisehjerter under fysiologiske forhold

Article DOI: 10.3791/60913-v • 07:54 min • March 20th, 2020
March 20th, 2020 •
*1, *1, 1, 1, 2, 2, 2, 2, 1, 1,3,4,5,6
1Institute of Molecular Cardiology, Department of Medicine, University of Louisville, 2Department of Bioengineering, University of Louisville, 3Diabetes and Obesity Center, Department of Medicine, University of Louisville, 4Department of Pharmacology and Toxicology, University of Louisville, 5Institute of Cardiovascular Sciences, University of Manchester, 6Faculty of Pharmacy, Zagazig University
* These authors contributed equally

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Denne protokol beskriver, hvordan man skive og kultur hjertevæv under fysiologiske forhold i 6 dage. Dette kultursystem kan bruges som en platform til at teste effekten af nye hjertesvigt terapeutiske samt pålidelig test af akut kardiotoksicitet i en 3D hjertemodel.

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Medicin genterapi kardiotoksicitet hjerte elektrisk stimulation calcium elektrofysiologi biomimetisk kultur farmakologi
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