Neonatal Hemodynamics

Neonatal hemodynamics is the study of blood flow, cardiac function, vascular resistance, and tissue perfusion in newborns, particularly during the transition from fetal to postnatal circulation. After birth, lung expansion lowers pulmonary vascular resistance, increases pulmonary blood flow, and shifts pressure gradients that close or reduce fetal pathways such as the ductus arteriosus and foramen ovale. Understanding these changes helps clinicians assess cardiac output, oxygen delivery, blood pressure, and organ perfusion in premature and critically ill infants. Hemodynamic evaluation supports diagnosis and management of conditions such as pulmonary hypertension, patent ductus arteriosus, shock, and ventricular dysfunction.

Neonatal Hemodynamics - Related Videos

Research

JoVE Journal - Medicine

Hemodynamic Precision in the Neonatal Intensive Care Unit using Targeted Neonatal Echocardiography

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Cited by 6 •

2023

Presented here is a protocol to perform comprehensive neonatal echocardiography by trained neonatologists in the neonatal intensive care unit. The trained individuals provide longitudinal assessments of heart function, systemic and pulmonary hemodynamics in a consultative role. The manuscript also describes the requirements to become a fully trained neonatal hemodynamics specialist.

Research

JoVE Journal - Medicine
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Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants

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Cited by 49 •

2013

We combined frequency-domain near-infrared spectroscopy measures of cerebral hemoglobin oxygenation with diffuse correlation spectroscopy measures of cerebral blood flow index to estimate an index of oxygen metabolism. We tested the utility of this measure as a bedside screening tool to evaluate the health and development of the newborn brain.

Transcutaneous Microcirculatory Imaging in Preterm Neonates

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Cited by 6 •

2015

Microcirculatory imaging (MI) is used to monitor peripheral perfusion in critically ill or preterm neonates. This manuscript and video demonstrates the optimal approach for obtaining high-quality images.

A Swine Model of Neonatal Asphyxia

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Cited by 50 •

2011

Large animal models have good translational values in the examination of physiology and pharmacology of neonatal asphyxia. Using newborn piglets, we develop an experimental protocol to simulate neonatal asphyxia which has advantages of studying the systemic and regional hemodynamics, oxygen transport with biochemical and pathologic pathways and correlations.

A Novel Ex Ovo Banding Technique to Alter Intracardiac Hemodynamics in an Embryonic Chicken System

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Cited by 2 •

2016

For the first time we present here a reproducible banding procedure to alter hemodynamics in the developing heart ex ovo. This is achieved by partially constricting the outflow tract (OFT).

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