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Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants
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Medicine
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JoVE Journal Medicine
Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants

Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants

DOI:
10.3791/4379-v

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11:39 min

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March 14, 2013

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, , , , , , , ,
1Athinoula A. Martinos Center for Biomedical Imaging,Massachusetts General Hospital, Harvard Medical School, 2Lab. PALM,Université de Caen Basse-Normandie, 3Fetal-Neonatal Neuroimaging and Developmental Science Center,Boston Children’s Hospital, Harvard Medical School, 4ISS, INC.

Chapters

  • 00:05Title
  • 02:45Preparation for Bedside Measures
  • 06:52Data Acquisition
  • 07:52Data Analysis
  • 09:10Optical Measurement Results
  • 11:03Conclusion

Summary

Automatic Translation

Automatic Translation

We combined frequency-domain near-infrared spectroscopy measures of cerebral hemoglobin oxygenation with diffuse correlation spectroscopy measures of cerebral blood flow index to estimate an index of oxygen metabolism. We tested the utility of this measure as a bedside screening tool to evaluate the health and development of the newborn brain.

Tags

Non-invasiveOptical MeasurementCerebral MetabolismHemodynamicsInfantsPerinatal Brain InjuryBedside ToolBrain HealthCMRO2Neuronal ViabilityDiagnostic InformationPositron Emission Tomography (PET)Single-photon Emission Computed Tomography (SPECT)RadionucleotidesContinuous-wave Near-infrared Spectroscopy (CWNIRS)Hemoglobin Oxygen Saturation (SO2)SurrogateCerebral Oxygen ConsumptionOxygen DeliveryBrain Injury

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