En-bloc Resection

En-bloc resection is a surgical technique that removes a lesion together with surrounding tissue or involved structures as a single specimen, rather than separating the components during removal. It works by maintaining the anatomical relationships around the target and dissecting through planned tissue planes while avoiding transection of the lesion itself. In medicine, particularly oncologic surgery, this approach can support complete excision, preserve specimen orientation for pathological margin assessment, and limit manipulation of diseased tissue. It is also used when adjacent organs or structures are involved, helping guide individualized treatment planning and prognostic evaluation.

En-bloc Resection - Related Videos

Research

JoVE EoE - Rodent Models

Roux-en-Y Gastric Bypass Procedure: A Bariatric Surgical Procedure for Gastric Resectioning in Murine Model

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2025

This video describes a bariatric surgery-Roux-en-Y procedure. This involves the cutting of the jejunum- the middle portion of the intestine- to generate two intestinal limbs. The biliary limb is attached to the existing intestinal loop and the alimentary limb is attached to the stomach, creating a gastric bypass. The gastric bypass created here helps to decrease the nutrient uptake and efficiently reduces body weight.

Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy

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2023

Numerous studies have demonstrated the advantages of anatomic resection. Nonetheless, whether anatomic resection can increase R0 resection rates remains controversial. Consequently, the present study describes an innovative procedure involving the en bloc concept combined with anatomic resection in laparoscopic hepatectomy, which can reduce postoperative recurrence and metastasis.

En Face Preparation of Mouse Blood Vessels

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Cited by 20 •

2017

A procedure for making en face preparations of the mouse carotid artery and aorta is described. Such preparations, when immunofluorescently stained with specific antibodies, enable us to study localization of proteins and identification of cell types within the entire vascular wall by confocal microscopy.

Brain Tumor Resection in a Mouse Using a Minimally Invasive Resection System

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2025

Source: Alomari, S., et al. Implementation of Minimally Invasive Brain Tumor Resection in Rodents for High Viability Tissue Collection. J. Vis. Exp. (2022)This video demonstrates the use of a minimally invasive resection system (MIRS) to excise tumor tissue from an anesthetized mouse implanted with a tumor. The procedure involves securing the mouse onto a stereotactic frame, reopening the previous surgical site to access the brain, and inserting a specialized cannula that utilizes suction and a...

Research

JoVE Journal - Cancer Research
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"Sun's Seven-Step Technique" for Endoscopic En-Bloc Resection of Thyroid Cancer via the Chest-Breast Approach

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2025

Endoscopic en bloc resection for thyroid carcinoma presents significant technical challenges, with current literature lacking comprehensive methodological descriptions. A systematic development and description of the "Sun's Seven-Step Technique" for endoscopic en-bloc thyroidectomy via the chest-breast approach was presented, demonstrating its superior operative efficiency, safety, and clinical feasibility.

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