Neurological Disorder Diagnosis

Neurological disorder diagnosis is the systematic identification of diseases affecting the brain, spinal cord, peripheral nerves, or muscles, enabling appropriate care and research. Clinicians combine medical history, neurological examination, and targeted tests to relate symptoms such as weakness, sensory loss, seizures, or cognitive changes to disrupted nervous system structure or function; magnetic resonance imaging, computed tomography, electroencephalography, electromyography, laboratory analysis, and genetic testing can provide complementary evidence. In neuroscience, this process distinguishes conditions with overlapping symptoms, supports prognosis and treatment selection, and improves understanding of disease mechanisms. Standardized diagnostic approaches also advance clinical trials and the development of biomarkers and therapies.

Neurological Disorder Diagnosis - Related Videos

Research

JoVE Journal - Neuroscience

Measuring Progressive Neurological Disability in a Mouse Model of Multiple Sclerosis

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Cited by 21 •

2016

An optimized testing protocol is presented in this paper for the Rotarod performance test, used for measuring progressive neurological disability in TMEV-infected mice.

Research

JoVE Journal - Medicine

Testing Acetylcholine Followed by Adenosine for Invasive Diagnosis of Coronary Vasomotor Disorders

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Cited by 6 •

2021

Coronary vasomotion disorders represent frequent functional causes of angina in patients with unobstructed coronaries. The underlying mechanism of angina (endotype) in these patients can be determined by a comprehensive invasive diagnostic procedure based on acetylcholine provocation testing followed by Doppler-derived assessment of the coronary flow reserve and microvascular resistance.

Research

JoVE Journal - Behavior
Free Sample

A Computer-Based Platform for Aiding Clinicians in Eating Disorder Analysis and Diagnosis

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2022

Diagnosing eating disorders in healthcare is challenging. Therefore, the present protocol develops an algorithm based on 949 patient responses to a questionnaire, with the diagnosis displayed on an easy-to-use web-based interface. This system facilitates the accurate diagnosis of eating disorders while excluding those believed to have an eating disorder.

Quantitative Analysis of Climbing Defects in a Drosophila Model of Neurodegenerative Disorders

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Cited by 122 •

2015

We present an optimized inexpensive and reliable negative geotaxis assay in Drosophila melanogaster as a model for neurodegenerative disorders. Being more sensitive to mild locomotor defects, this assay will help screen for potential genetic interactions and drug targets.

Education

JoVE Core - Introduction to Psychology

Diagnostic and Statistical Manual of Mental Disorders (DSM)

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2026

The Diagnostic and Statistical Manual of Mental Disorders (DSM) serves as the primary classification system for mental health disorders, providing standardized diagnostic criteria for clinicians and researchers. First published by the American Psychiatric Association (APA) in 1952, the DSM has undergone several revisions to reflect evolving psychiatric understanding. The fifth edition, DSM-5, was published in 2013, followed by its text revision, DSM-5-TR, in 2022. This revision incorporates...

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