Testing Acetylcholine Followed by Adenosine for Invasive Diagnosis of Coronary Vasomotor Disorders

The invasive diagnostic procedure, the so-called IDP, allows to identify functional coronary diseases, which are frequent mechanisms of angina in patients with unobstructed coronary arteries. The IDP provides a comprehensive evaluation of the dilatory and constrictive component of coronary vasomotion using intracoronary flow and pressure measurements. This is done at rest and during hyperemia, and also coronary spasm testing is performed.

There are different subtypes of functional coronary diseases, which are associated with different prognosis and treatment recommendations. The IDP helps to make the diagnosis and to find the optimal treatment. Begin by placing a guiding catheter suitable for the left coronary artery into the left main artery, and deliver another 5, 000 international units of heparin.