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JoVE Journal Bioengineering
Concentric Gel system att studera den Biofysikalisk roll Matrix mikromiljö på 3D Cell Migration
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Concentric Gel system att studera den Biofysikalisk roll Matrix mikromiljö på 3D Cell Migration

Article DOI: 10.3791/52735-v • 11:43 min • April 3rd, 2015
April 3rd, 2015 •
1, 2, 2,3
1Systems Biophysics Department, FOM Institute AMOLF, 2Mechanobiology Institute, National University of Singapore, 3Department of Biomedical Engineering, National University of Singapore

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De mekaniska egenskaperna och mikrostrukturen hos den extracellulära matrisen påverkar starkt 3D migration av celler. En in vitro-metod för att studera spatiotemporal cellmigration beteende biofysiskt variabla miljöer, både befolkning och enskilda cellnivå, beskrivs.

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Bioteknik cellmigration kollagen biomekanik 3D cellodling live-cell imaging cancerinvasion metastaser extracellulär matrix porstorlek biopolymerer cytoskelettet konfokalmikroskopi
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