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In Vivo Évaluation des EPR du pH, pO2, statut Redox et les Concentrations de Phosphate et de glutathion dans le microenvironnement tumoral

Article DOI: 10.3791/56624-v • 10:46 min • March 16th, 2018
March 16th, 2018 •
1,2, 1,3, 1,2, 1,2
1In Vivo Multifunctional Magnetic Resonance center, Robert C. Byrd Health Sciences Center, West Virginia University, 2Department of Biochemistry, West Virginia University School of Medicine, 3Department of Microbiology, Immunology & Cell Biology, West Virginia University School of Medicine

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La résonance paramagnétique électronique champ faible (bande L, 1,2 GHz) à l’aide des sondes nitroxyles et trityle solubles est démontrée pour l’évaluation des paramètres physiologiques importants dans le microenvironnement tumoral dans des modèles murins de cancer du sein.

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Recherche sur le cancer numéro 133 résonance paramagnétique électronique nitroxyde trityle radical pH concentration en oxygène statut redox glutathion phosphate inorganique microenvironnement tumoral
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