Group Housed Mice

Group housed mice are laboratory mice maintained together in shared enclosures, an arrangement that models a social environment and can strongly influence behavioral outcomes. Through repeated social interactions, mice establish relationships and dominance hierarchies, while olfactory cues, competition for resources, and access to shelter shape activity, aggression, anxiety-like behavior, and stress responses. Studying group housed mice helps researchers assess social behavior and welfare while improving the interpretation of experiments in neuroscience, psychology, and disease research. Careful control and reporting of group size, sex, strain, cage conditions, and social composition are essential for reproducible results and for distinguishing treatment effects from housing-related influences.

Group Housed Mice - Related Videos

Research

JoVE Journal - Medicine

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure

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Cited by 7 •

2017

This study describes the successful generation of a new chronic obstructive pulmonary disease (COPD) animal model by repeatedly exposing mice to high concentrations of ozone.

Research

JoVE Journal - Medicine
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Measuring the Strength of Mice

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Cited by 287 •

2013

Deficits in muscular strength occur in many clinical conditions such as motor neuron disease. The inverted screen and weight lifting tests described here measure strength in mice almost exclusively, with minimal influence of factors such as coordination.

Small Bowel Transplantation In Mice

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Cited by 2 •

2007

The mouse small bowel transplantation model has been recognized as an important tool to study mechanismes of immune rejection and screen new immunosuppressive drugs. However, this model is limited to use because the techniques involved is an extremely technically challenge. Now we introduce the modified technique.

Trace Fear Conditioning in Mice

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Cited by 32 •

2014

In the following experiment we describe a protocol for trace fear conditioning in mice. This type of associative memory includes a trace period that separates the neutral stimulus and the unconditioned stimulus.

Research

JoVE Journal - Neuroscience
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Video-oculography in Mice

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Cited by 24 •

2012

Video-oculography is a very quantitative method to investigate ocular motor performance as well as motor learning. Here, we describe how to measure video-oculography in mice. Applying this technique on normal, pharmacologically-treated or genetically modified mice is a powerful research tool to explore the underlying physiology of motor behaviors.

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