Songbird Brain

The songbird brain is a specialized vertebrate nervous system that supports vocal learning, song production, auditory perception, and other behaviors, making it a valuable model for studying how brains generate and modify behavior. During song learning, auditory circuits compare a young bird’s vocalizations with memorized or heard songs, while interconnected motor regions guide vocal output and adjust it through feedback. Research on songbirds has revealed how experience, development, hormones, and seasonal changes can reshape neural circuits and behavior. These findings inform broader studies of learning, memory, neural plasticity, communication, and the biological basis of behavioral change.

Songbird Brain - Related Videos

Research

JoVE Journal - Behavior

Functional Magnetic Resonance Imaging (fMRI) with Auditory Stimulation in Songbirds

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Cited by 12 •

2013

This article shows an optimized procedure for imaging of the neural substrates of auditory stimulation in the songbird brain using functional Magnetic Resonance Imaging (fMRI). It describes the preparation of the sound stimuli, the positioning of the subject and the acquisition and subsequent analysis of the fMRI data.

Research

JoVE Journal - Neuroscience
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A Lightweight, Headphones-based System for Manipulating Auditory Feedback in Songbirds

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Cited by 14 •

2012

We describe the design and assembly of miniaturized headphones suitable for replacing a songbird’s natural auditory feedback with a manipulated acoustic signal. Online sound processing hardware is used to manipulate song output, introduce real-time errors in auditory feedback via the headphones, and drive vocal motor learning.

Double Fluorescence in situ Hybridization in Fresh Brain Sections

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Cited by 7 •

2010

This protocol involves a non-radioactive in-situ hybridization procedure that enables the simultaneous identification of two transcript species, at a single cell resolution, in thin sections of the vertebrate brain.

Isolating Immune Cells from Mouse Brain and Skull

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Cited by 1 •

2024

To investigate the immune response to brain disorders, one common approach is to analyze changes in immune cells. Here, two simple and effective protocols are provided for isolating immune cells from murine brain tissue and skull bone marrow.

Improved Method for the Establishment of an In Vitro Blood-Brain Barrier Model Based on Porcine Brain Endothelial Cells

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Cited by 31 •

2017

The aim of the protocol is to present an optimized procedure for the establishment of an in vitro blood-brain barrier (BBB) model based on primary porcine brain endothelial cells (pBECs). The model shows high reproducibility, high tightness, and is suitable for studies of transport and intracellular trafficking in drug discovery.

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