Timing Automation

Timing automation is the programmed control of when actions occur, allowing processes to run at defined intervals, in a specific sequence, or in response to measured conditions. In bioengineering, automated systems use clocks, timers, sensors, and control software to coordinate operations such as reagent addition, sampling, temperature changes, and instrument activation while reducing manual intervention. This approach improves reproducibility, supports precise multistep protocols, and helps maintain consistent experimental conditions. Timing automation is useful in bioprocessing, cell culture, diagnostic workflows, and laboratory instrumentation, where synchronized events can increase throughput, limit operator error, and enable reliable collection of time-dependent biological data.

Timing Automation - Related Videos

Research

JoVE Journal - Biochemistry

Automated Acoustic Dispensing for the Serial Dilution of Peptide Agonists in Potency Determination Assays

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Cited by 1 •

2016

Peptide adsorption to plasticware during traditional tip-based serial dilutions can significantly impact potency determination and confound the understanding of structure-activity relationships used for lead identification and lead optimization phases of drug discovery. Here methods for automated acoustic non-contact serial dilution of peptide samples are described.

An Automated Method to Determine the Performance of Drosophila in Response to Temperature Changes in Space and Time

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Cited by 4 •

2018

Here we present a protocol to automatically determine the locomotor performance of Drosophila at changing temperatures using a programmable temperature-controlled arena that produces fast and accurate temperature changes in time and space.

Research

JoVE Journal - Immunology and Infection
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Live Cell Imaging of Bacillus subtilis and Streptococcus pneumoniae using Automated Time-lapse Microscopy

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Cited by 157 •

2011

This protocol provides a step-by-step procedure to monitor single cell behavior of different bacteria in time using automated fluorescence time-lapse microscopy. Furthermore, we provide guidelines how to analyze the microscopy images.

Research

JoVE Journal - Chemistry
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Technical Aspect of the Automated Synthesis and Real-Time Kinetic Evaluation of [11C]SNAP-7941

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Cited by 2 •

2019

Here, we represent a protocol for the fully automated radiolabelling of [11C]SNAP-7941 and the analysis of the real-time kinetics of this PET-tracer on P-gp expressing and non-expressing cells.

An Automated Squint Method for Time-syncing Behavior and Brain Dynamics in Mouse Pain Studies

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Cited by 1 •

2024

This protocol provides a method for tracking automated eye squint in rodents over time in a manner compatible with time-locking to neurophysiological measures. This protocol is expected to be useful to researchers studying mechanisms of pain disorders such as migraine.

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