Cranial Region

The cranial region is the anatomical area of the head associated with the skull, brain, facial structures, and major sensory organs, making it central to nervous system function and organismal interaction with the environment. Its bones and connective tissues form a protective cranial cavity, while openings and specialized structures allow passage of blood vessels, nerves, and the spinal cord and support vision, hearing, smell, and movement. In biology, studying the cranial region helps researchers understand brain protection, skull development, facial anatomy, neurological disorders, injury, and evolutionary changes in vertebrate form and function.

Cranial Region - Related Videos

Research

JoVE EoE - Cancers of the Nervous System

Implantation of Cranial Imaging Window in Mouse Model: A Surgical Procedure to Implant Glass-based Coverslip for Stable Optical Access to Regions of Murine Brain

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2023

This video presents a surgical procedure to implant cranial window in a mouse model for stable optical access to different regions of the brain.

A Method for 2-Photon Imaging of Blood Flow in the Neocortex through a Cranial Window

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Cited by 50 •

2008

Cortical blood flow dynamics can be studied in vivo by imaging fluorescent dextran dyes injected into the tail vein of rodents with 2-photon microscopy. This video shows how to image blood flow dynamics in neocortex of mice through a glass-covered cranial window preparation.

Research

JoVE Journal - Biology
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An Explant Assay for Assessing Cellular Behavior of the Cranial Mesenchyme

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Cited by 2 •

2013

The cranial mesenchyme undergoes dramatic morphogenic movements that likely provides a driving force for elevation of the neural folds1,2. Here we describe a simple ex vivo explant assay to characterize the cellular behaviors of the cranial mesenchyme during neurulation. This assay has numerous applications including being amenable to pharmacological manipulations and live imaging analyses.

Education

JoVE Core - Analytical Chemistry

IR Frequency Region: Fingerprint Region

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2024

IR spectra are divided into two main regions: the diagnostic region and the fingerprint region. The diagnostic region of the spectrum lies above 1500 cm−1. The absorptions resulting from single-bond vibrations of the N–H, C–H, and O–H stretch at higher wavenumbers and appear on the left side of the spectrum. The stretching absorptions of the C≡C and C≡N occur between 2100–2300 cm−1. In contrast, those arising from stretching absorptions of the C=O, C=N, and C=C occur between 1600–1850 cm−1. The...

Research

JoVE Journal - Medicine
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Quantifying Cognitive Decrements Caused by Cranial Radiotherapy

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Cited by 6 •

2011

Cognitive impairment resulting from the radiotherapeutic management of brain tumors represents a clinically intractable condition that adversely impacts quality of life. The capability to critically evaluate potential interventions for ameliorating radiation-induced cognitive decrements ultimately depends on the capability to undertake rigorous quantitative assessments of cognition.

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