Electrode Assembly

Electrode assembly is the process of constructing and integrating conductive components that detect electrical activity or deliver controlled stimulation in biological systems. It typically combines an electrode material, an insulating layer, and electrical connections so that exposed conductive surfaces interface with cells, tissues, or physiological fluids while limiting unwanted current leakage. In biology, carefully assembled electrodes support electrophysiological recording, neural stimulation, biosensing, and measurements of muscle or cardiac activity. Assembly quality influences signal strength, noise, biocompatibility, and placement stability, making it important for reliable experiments, diagnostic devices, and research on how electrical signals regulate cellular and organ function.

Electrode Assembly - Related Videos

Research

JoVE EoE - Neurophysiology

Implantation of an Electrode Assembly in a Mouse Brain for Electrophysiological Recording

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2025

This video demonstrates a technique for implanting an electrode assembly into a mouse brain. The assembly contains bipolar electrodes to record activity from the hippocampus and a reference electrode to obtain baseline activity from the cerebellum. An anesthetized mouse is placed on a stereotaxic frame, and the electrode assembly is implanted in the target brain region. The animal is then allowed to recover before performing electrophysiological recording.

Fabrication of Amperometric Electrodes

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Cited by 8 •

2009

This protocol describes how to generate carbon fiber electrodes. The electrodes are subsequently used to detect catecholamine release from vesicles with carbon fiber amperometry.

Research

JoVE Journal - Biology
Free Sample

Assembly, Loading, and Alignment of an Analytical Ultracentrifuge Sample Cell

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Cited by 21 •

2009

The analytical ultracentrifuge (AUC) sample cell holds sample and reference buffer and during experiments and is exposed to high vacuum and rotor speeds up to 60,000 rpm. This video will demonstrate the rigorous attention to detail necessary for assembly, loading and alignment of this very important component of an AUC experiment.

Education

JoVE Core - Chemistry

Standard Electrode Potentials

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2020

On comparing the reactivity of silver and lead, it is observed that the two ionic species, Ag+ (aq) and Pb2+ (aq), show a difference in their redox reactivity towards copper: the silver ion undergoes spontaneous reduction, while the lead ion does not. This relative redox activity can be easily quantified in electrochemical cells by a property called cell potential. This property is commonly known as cell voltage in electrochemistry, and it is a measure of the energy which accompanies the charge...

Implanting an Electrode into the Subthalamic Nucleus of a Rat

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2025

The video demonstrates a procedure for implanting an electrode into the subthalamic nucleus of a rat to deliver electrical stimuli.

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