Left Ventricle Dimensions

Left ventricle dimensions describe the chamber’s size and wall geometry, providing important indicators of cardiac structure and function. These measurements commonly include internal diameter, wall thickness, length, and volume, which change between diastole, when the ventricle fills, and systole, when it contracts to eject blood into the aorta. Echocardiography and other cardiac imaging methods quantify these features and can be combined with functional measures such as ejection fraction. In biology and clinical research, left ventricle dimensions help assess cardiac development, remodeling, hypertrophy, dilation, and the effects of cardiovascular disease or treatment.

Left Ventricle Dimensions - Related Videos

Research

JoVE EoE - Rodent Models

Transverse Aortic Arch Banding in Mouse Model: A Minimally Invasive Technique in Mice for Induction of High Pressure in the Left Ventricle

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2025

In this video, we demonstrate an experimental protocol for minimally invasive transverse aortic constriction in mice to examine pressure overload-induced heart failure.

Zebrafish Brain Ventricle Injection

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Cited by 73 •

2009

After neural tube formation, the neuroepithelium constricts and folds while the tube fills with embryonic cerebrospinal fluid (eCSF) to form the embryonic brain ventricles. We developed this ventricle injection technique to better visualize the fluid filled space in contrast to the neuroepithelial shape in a live embryo.

Real-Time Detection of Ferulic Acid Effects on Rat Left Ventricle Using Pressure-Volume Conductivity Catheter

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2024

This protocol describes a method for measuring left ventricular pressure and volume using the pressure-volume conductance technique. This method enables continuous real-time monitoring of the effects of drugs on the heart.

Manual Drainage of the Zebrafish Embryonic Brain Ventricles

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Cited by 9 •

2012

We present a method to collect cerebrospinal fluid (CSF) and to create a system which lacks CSF within the embryonic zebrafish brain ventricular system. This allows for further examination of CSF composition and its requirement during embryonic brain development.

3D Modeling of the Lateral Ventricles and Histological Characterization of Periventricular Tissue in Humans and Mouse

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Cited by 17 •

2015

Using MRI scans (human), 3D imaging software, and immunohistological analysis, we document changes to the brain’s lateral ventricles. Longitudinal 3D mapping of lateral ventricle volume changes and characterization of periventricular cellular changes that occur in the human brain due to aging or disease are then modeled in mice.

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