Lung Volumes

Lung volumes are measurements of the amount of air moving into, out of, and remaining within the lungs during breathing, providing important information about respiratory function. They include tidal volume, inspiratory and expiratory reserve volumes, and residual volume, which together describe how the lungs respond to changes in pressure and airflow during quiet and forced breathing. Spirometry measures several of these volumes and capacities by recording airflow while a person performs controlled respiratory maneuvers, although residual volume requires methods such as gas dilution or body plethysmography. In biology and clinical research, these measurements help assess ventilation, identify restrictive or obstructive patterns, and evaluate respiratory changes across health conditions.

Lung Volumes - Related Videos

Research

JoVE Journal - Medicine

Measurement of the Pressure-volume Curve in Mouse Lungs

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Cited by 47 •

2015

Here we present a protocol to simply and reliably measure the lung pressure-volume curve in mice, showing that it is sufficiently sensitive to detect phenotypic parenchymal changes in two common lung pathologies, pulmonary fibrosis and emphysema. This metric provides a means to quantify the lung’s structural changes with developing pathology.

Lung Instillation and Fixation: Introducing Liquid into the Trachea and Fixing Lungs to Measure the Fixed Lung Volume

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2023

This video describes a simple and reliable method of introducing liquid into the trachea for lung instillation, fixation, and lung volume measurement.

Real-time X-ray Imaging of Lung Fluid Volumes in Neonatal Mouse Lung

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Cited by 1 •

2016

We present a protocol to assess the rate of alveolar fluid clearance or pulmonary edema in neonatal mouse lung using X-ray imaging technology.

Rat Heterotopic Abdominal Heart/Single-lung Transplantation in a Volume-loaded Configuration

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2015

We describe a novel technique for heterotopic abdominal heart-lung transplantation (HAHLT) in rats. The transplant configuration results in a partially loaded graft circulation, allowing direct functional assessment. This model may be employed for acute or chronic studies of function and immunologic status of the transplanted graft.

Education

JoVE Core - Biology

Lung Capacity

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2019

The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures. There are four defined lung volume measures: tidal volume, inspiratory reserve volume, expiratory reserve volume, and residual volume. Tidal volume is the amount of air inhaled and exhaled in a normal breath. Inspiratory...

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