Mobile Genetic Elements
Mobile Genetic Elements - Related Videos
04:00
Periodic Classification of the Elements
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2020
The periodic table arranges atoms based on increasing atomic number so that elements with the same chemical properties recur periodically. When their electron configurations are added to the table, a periodic recurrence of similar electron configurations in the outer shells of these elements is observed. Because they are in the outer shells of an atom, valence electrons play the most important role in chemical reactions. The outer electrons have the highest energy of the electrons in an atom...
02:54
Classification of Elements and Compounds
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2020
Pure substances consist of only one type of matter. A pure substance can be an element or a compound. An element consists of only one type of atom, while a compound consists of two or more types of atoms held together by a chemical bond. Elements are classified as atomic or molecular based on the nature of their basic units. Compounds are pure substances composed of two or more elements in fixed, definite proportions. Compounds are classified as ionic or molecular (covalent) based on the bonds...
11:35
Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay (EMSA) and DNA-affinity Precipitation Assay (DAPA)
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Cited by 15 •
2016
We present a strategic plan and protocol for identifying non-coding genetic variants affecting transcription factor (TF) DNA binding. A detailed experimental protocol is provided for electrophoretic mobility shift assay (EMSA) and DNA affinity precipitation assay (DAPA) analysis of genotype-dependent TF DNA binding.
08:50
Genetic Screens
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2023
Genetic screens are critical tools for defining gene function and understanding gene interactions. Screens typically involve mutating genes and then assessing the affected organisms for phenotypes of interest. The process can be “forward”, where mutations are generated randomly to identify unknown genes responsible for the phenotypes, or it can be “reverse”, where specific genes are targeted for mutation to observe what phenotypes are produced.Here, JoVE reviews various types of genetic...
02:31
Elements: Chemical Symbols and Isotopes
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2020
A chemical symbol is an abbreviation used to indicate an element or an atom of an element. For example, the symbol for mercury is Hg. The same symbol is used to indicate one atom of mercury (microscopic domain) or to label a container of many atoms of the element mercury (macroscopic domain). Some symbols are derived from the common English name of the element; others are abbreviations of the name in another language — Latin, Greek or German. For example, the symbol for aluminum (common name)...
FAQs
Cut-and-paste transposition moves a DNA segment from one genomic location to another, whereas copy-and-paste transposition leaves the original sequence in place while generating an additional copy elsewhere. This distinction affects whether the genome loses, gains, or redistributes genetic material, helping explain different patterns of genome organization and variation.
An insertion can alter gene expression when it occurs within or near a gene or its regulatory region. The resulting change may disrupt existing genetic information or modify how strongly a gene is expressed. Consequently, the same mobilization process can produce different biological outcomes depending on the DNA location affected.
Movement within a genome changes the arrangement of DNA in a single cell's genetic material. Horizontal gene transfer, in contrast, moves transferable genetic material between cells. Plasmids and related systems are important in this broader process because they can distribute genetic information across cells, contributing to microbial adaptation and evolution.
These elements can help genetic information associated with new traits move through microbial populations. When transferable systems distribute information that contributes to antibiotic resistance, resistance can spread beyond the original cell or lineage. Studying this process connects genome mobility with microbial evolution and helps explain how resistance patterns emerge.
Analysis can reveal how genomes are organized, how genetic variation arises, and how organisms adapt over evolutionary time. Researchers can also examine whether an element's insertion changes gene expression or introduces a new trait. These observations connect molecular changes in DNA with broader patterns of genome evolution and microbial diversification.
Their ability to alter DNA locations or influence gene activity makes these systems relevant to genetic engineering and functional genomics. Researchers can use them as biological tools for examining gene function and genome organization. In this context, mobile elements provide a link between controlled DNA manipulation and the study of how genetic changes affect biological traits.