Neural Connection
Neural Connection - Related Videos
03:25
Two-Photon Holographic Microscopy to Study Neural Activity and Connectivity in a Mouse Model
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2025
Source: Kato, D. et. al., Evaluation and Manipulation of Neural Activity Using Two-Photon Holographic Microscopy. J. Vis. Exp. (2022)This video demonstrates the two-photon imaging technique combined with optogenetics using holographic microscopy. Using a spatial light modulator, this technique enables precise neuronal stimulation expressing the red-light-sensitive protein and calcium imaging with minimal photodamage. This approach provides insights into the functional connectivity and...
02:17
Assessing Neural Connection Formation in a Co-Culture using Electrophysiological Recordings
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2025
The video demonstrates electrophysiological recording to assess neural connections between iPSC-derived and rat cortical neurons, confirming synaptic contacts in the co-culture by activating light-sensitive ion channels and detecting postsynaptic currents.
06:50
Analyzing Neural Activity and Connectivity Using Intracranial EEG Data with SPM Software
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Cited by 1 •
2018
We present two analytical protocols that can be used to analyze intracranial electroencephalography data using the Statistical Parametric Mapping (SPM) software: time-frequency statistical parametric mapping analysis for neural activity, and dynamic causal modeling of induced responses for intra- and inter-regional connectivity.
10:32
Enumeration of Neural Stem Cells Using Clonal Assays
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Cited by 5 •
2016
Neural stem cells (NSCs) refer to cells which can self-renew and differentiate into the three neural lineages. Here, we describe a protocol to determine NSC frequency in a given cell population using neurosphere formation and differentiation under clonal conditions.
01:23
Dietary Connections
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2019
In biological systems, most metabolic pathways are interconnected. The cellular respiration processes that convert glucose to ATP—such as glycolysis, pyruvate oxidation, and the citric acid cycle—tie into those that break down other organic compounds. As a result, various foods—from apples to cheese to guacamole—end up as ATP. In addition to carbohydrates, food also contains proteins and lipids—such as cholesterol and fats. All of these organic compounds are used as energy sources to produce...
FAQs
At a chemical synapse, an electrical signal traveling along the axon reaches the terminal and triggers neurotransmitter release. The molecules cross the narrow gap and bind receptors on the next cell. This sequence converts an incoming electrical event into receptor-mediated signaling, allowing one neuron’s activity to influence another cell and helping organize information flow through circuits.
Neurotransmitters do not produce a single uniform response. After release, their binding to receptors on the receiving cell can either increase or decrease that cell’s activity. This opposing influence allows connected neurons to regulate one another rather than simply pass signals onward. Balanced increases and decreases help circuits process information and coordinate outputs.
A neural connection may link one neuron to another neuron, a muscle, or a gland. Consequently, the same general signaling process can contribute to information processing, movement, or glandular activity, depending on the connected cells. Identifying the target is therefore important when interpreting what a connection does within a biological circuit.
Plasticity refers to the capacity of neural connections or circuits to change over time. Because circuits can be modified rather than remaining fixed, signaling patterns may contribute to learning, memory, and behavior. In biology research, examining plasticity alongside connection development helps explain how nervous-system organization changes and how these functions emerge.
Research commonly focuses on three linked aspects: how connections develop, how signals are transmitted, and how circuit organization changes through plasticity. Considering these dimensions together connects cellular signaling with larger functions such as sensation, movement, learning, memory, and behavior. This approach also provides a framework for relating connection properties to overall nervous-system function.
Neural connections provide a way to study links between cellular communication and nervous-system dysfunction. Research on their development, signaling, and plasticity may clarify how circuit-level problems affect sensation, movement, learning, memory, or behavior. These findings can also inform investigations of potential therapeutic strategies by identifying biological processes relevant to neurological disorders.