Resource Limited Settings

Resource-limited settings are environments where restricted funding, infrastructure, equipment, supplies, or trained personnel constrain biological research, healthcare, and public-health activities. In these settings, investigators and practitioners adapt workflows by prioritizing essential measurements, using robust low-cost methods, simplifying sample processing, and matching protocols to available electricity, laboratory space, and supply chains. This approach supports disease surveillance, diagnostic testing, ecological monitoring, and implementation of biology-based interventions when conventional facilities are unavailable. Studying biology in resource-limited settings also reveals how methods perform under real-world conditions and guides the development of affordable, scalable tools that can improve scientific and health outcomes.

Resource Limited Settings - Related Videos

Research

JoVE Journal - Medicine
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An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings

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Cited by 37 •

2014

Drug resistance testing for HIV-1 infected individuals failing antiretroviral therapy (ART) can guide future therapies and improve treatment outcomes. Optimizing individual and population health outcomes in high HIV prevalence but resource-limited settings will ultimately require affordable and accessible drug resistance genotyping and interpretation methods.

Research

JoVE Journal - Engineering

Setting Limits on Supersymmetry Using Simplified Models

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Cited by 6 •

2013

This paper demonstrates a protocol for recasting experimental simplified model limits into conservative and aggressive limits on an arbitrary new physics model. Publicly available LHC experimental results can be recast in this manner into limits on almost any new physics model with a supersymmetry-like signature.

Field Postmortem Rabies Rapid Immunochromatographic Diagnostic Test for Resource-Limited Settings with Further Molecular Applications

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Cited by 25 •

2020

We present a complete protocol for postmortem diagnosis of animal rabies under field conditions using a rapid immunochromatographic diagnostic test (RIDT), from brain biopsy sampling to final interpretation. We also describe further applications using the device for molecular analysis and viral genotyping.

Education

JoVE Business - Finance

Choosing Between Projects: Limited Resources

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2024

In capital budgeting, selecting positive NPV projects adds value to a company. Although businesses ideally pursue all positive NPV projects, managers often face budget constraints that limit the amount of capital they can invest within a given period. In such cases, the goal is to maximize the total NPV while staying within budget limits. For example, a chocolate manufacturing company has a $100,000 budget and two projects under consideration. Project A requires an investment of $80,000, with...

Open-Source Miniature Fluorimeter to Monitor Real-Time Isothermal Nucleic Acid Amplification Reactions in Resource-Limited Settings

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Cited by 5 •

2021

Detailed instructions are provided to build an open-source, modular fluorimeter that is compatible with many low-cost heaters to perform real-time, quantitative isothermal nucleic acid amplification.

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