Sacral Spinal Segments

Sacral spinal segments are the lower spinal cord regions associated with sacral spinal nerves, which coordinate sensation, movement, and autonomic functions in the pelvis and lower limbs. Although the spinal cord typically ends above the sacrum, sacral nerve roots descend through the vertebral canal as part of the cauda equina before exiting at sacral foramina; segments S2–S4 also provide parasympathetic control of the bladder, bowel, and sexual organs. Studying these segments helps explain pelvic reflexes, lower-limb innervation, and patterns of neurological injury. Their anatomy is important in clinical examination, spinal trauma assessment, neurosurgery, and treatments involving sacral nerve stimulation.

Sacral Spinal Segments - Related Videos

Research

JoVE Journal - Neuroscience

Retrograde Loading of Nerves, Tracts, and Spinal Roots with Fluorescent Dyes

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Cited by 5 •

2012

We describe a simple and low cost technique for introducing high concentration of fluorescent and calcium-sensitive dyes into neurons or any neuronal tract using a polyethylene suction pipette.

Two-photon Imaging of Cellular Dynamics in the Mouse Spinal Cord

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Cited by 5 •

2015

A new ex vivo preparation for imaging the mouse spinal cord. This protocol allows for two-photon imaging of live cellular interactions throughout the spinal cord.

Acute and Chronic Tactile Sensory Testing after Spinal Cord Injury in Rats

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Cited by 55 •

2012

We describe two tactile sensory testing methods for acute or chronic periods of spinal cord injury in rats. These validated procedures can detect the development and maintenance of allodynia-like sensations.

Spinal Cord Electrophysiology

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Cited by 5 •

2010

A demonstration of the isolation of neonatal mouse spinal cord for electrophysiologic studies.

Trans-Spinal Direct Current Stimulation of a Rat's Spinal Motoneuron

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2025

This video describes the in vivo intracellular recording of rat motoneurons under trans-spinal direct current stimulation. The protocol describes how to measure membrane properties and record the rhythmic firing of motoneurons before, during, and after anodal or cathodal polarization of the spinal cord.

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