Sublimation
Sublimation - Related Videos
05:39
Purification of Ferrocene by Sublimation
0 Views •
2023
Source: Tamara M. Powers, Department of Chemistry, Texas A&M University Sublimation, the direct phase transition of a solid into a gas without first becoming a liquid, takes place at temperatures and pressures lower than that of the compound's triple point (Figure 1).The process of sublimation can be utilized to purify both organic and inorganic solids. During the purification technique, a solid is heated directly into the gas-phase. All non-volatile impurities are left behind while the...
02:33
Phase Transitions: Sublimation and Deposition
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2020
Some solids can transition directly into the gaseous state, bypassing the liquid state, via a process known as sublimation. At room temperature and standard pressure, a piece of dry ice (solid CO2) sublimes, appearing to gradually disappear without ever forming any liquid. Snow and ice sublimate at temperatures below the melting point of water, a slow process that may be accelerated by winds and the reduced atmospheric pressures at high altitudes. When solid iodine is warmed, the solid sublimes...
01:03
Sublimation
0 Views •
2024
Sublimation is the direct transformation of a solid to a gaseous state. For instance, at standard pressure and room temperature, solid carbon dioxide sublimes to gaseous carbon dioxide. The phase diagram depicts the conditions required for sublimation. This process occurs at the solid-gas phase boundary and is not observed above the triple point of the substance. The reverse of sublimation is called deposition, where a gaseous substance condenses directly into a solid. Sublimation and...
08:36
Sublimation of DAN Matrix for the Detection and Visualization of Gangliosides in Rat Brain Tissue for MALDI Imaging Mass Spectrometry
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Cited by 43 •
2017
A protocol for the sublimation of DAN matrix onto rat brain tissue for the detection of gangliosides using MALDI Imaging Mass Spectrometry is presented.
12:21
Close-Space Sublimation-Deposited Ultra-Thin CdSeTe/CdTe Solar Cells for Enhanced Short-Circuit Current Density and Photoluminescence
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Cited by 6 •
2020
This work describes the complete fabrication process of thin absorber cadmium selenium telluride/cadmium telluride photovoltaic devices for enhanced efficiency. The process utilizes an automated in-line vacuum system for close-space sublimation deposition that is scalable, from fabrication of small area research devices as well as large-scale modules.
FAQs
Reduced pressure and controlled temperature help biological samples avoid liquid formation while molecules leave the solid phase. This control is especially important during lyophilization because the material begins in a frozen state and must lose ice without exposing the sample to conditions that could compromise its preserved structure or activity.
The process removes ice from frozen biological materials while helping retain their structure and activity. That preservation is valuable for temperature-sensitive samples, because maintaining these properties supports later storage, transport, and experimental use. Its importance therefore depends not only on removing water as ice, but also on protecting the biological characteristics researchers need.
Sublimation-based drying avoids the liquid stage by removing ice directly from a frozen material. In biological preservation, this pathway is used in lyophilization to limit the changes associated with liquid formation. The distinction matters because the method is designed to remove ice while helping preserve the structure and activity of sensitive cells, proteins, vaccines, and related samples.
Sublimation begins when molecules in a solid gain enough energy to escape into the gas phase. Temperature control therefore influences whether molecules can leave the solid, while pressure conditions help prevent the formation of a liquid state. In biological applications, managing both factors supports controlled ice removal from frozen samples rather than uncontrolled phase change.
Lyophilization starts with a biological material in a frozen state, followed by conditions that remove its ice through sublimation. The process is controlled so the sample avoids liquid formation while losing the frozen component. This workflow is applied to cells, proteins, vaccines, and other temperature-sensitive materials when preservation is needed for storage, transport, or later experiments.
Researchers may choose lyophilization when a biological sample is temperature-sensitive and must retain useful structure or activity during preservation. The approach is relevant for cells, proteins, vaccines, and other biological materials that require long-term storage or transport. It also supports experimental work by making preserved samples available for later use.
Sublimation-based preservation can produce biological samples that remain suitable for long-term storage, transport, and experimental use. For frozen cells, proteins, vaccines, and related materials, removing ice while helping maintain structure and activity supports continued access to the sample. These outcomes make the process useful wherever temperature-sensitive biological materials must be preserved beyond immediate handling.