Tooth Socket Healing

Tooth socket healing is the biological repair process that restores the gum and supporting bone after a tooth is removed. It begins when a blood clot forms in the socket, followed by inflammation, migration of repair cells, and growth of granulation tissue that gradually supports new blood vessels and connective tissue. The wound then undergoes epithelial closure, bone formation, and long-term remodeling as the newly formed tissue matures. Understanding these coordinated stages helps biology and dental researchers evaluate recovery, identify factors that delay healing, and improve approaches to tooth extraction, implant placement, and treatment of oral wounds.

Tooth Socket Healing - Related Videos

Research

JoVE Journal - Biology

The Establishment of a Murine Mandibular Molar Extraction Socket Healing Model

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Cited by 1 •

2023

This protocol demonstrates step-by-step details of how to extract the mandibular first molar in the mouse. It provides an alternative method for researchers focusing on jawbone healing and regeneration.

In situ Compressive Loading and Correlative Noninvasive Imaging of the Bone-periodontal Ligament-tooth Fibrous Joint

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Cited by 17 •

2014

In this study, the use of an in situ loading device coupled with micro-X-ray computed tomography for fibrous joint biomechanics will be discussed. Experimental readouts identifiable with an overall change in joint biomechanics will include: 1) reactionary force vs. displacement, i.e. tooth displacement within the alveolar socket and its reactionary response to loading, 2) three-dimensional (3D) spatial configuration and morphometrics, i.e. geometric relationship of the tooth with the alveolar...

A Device for Performing Cell Migration/Wound Healing in a 96-Well Plate

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Cited by 7 •

2017

Here, we present a protocol to perform a semi-high throughput cell migration assay on a 96-well cell culture plate. This protocol is a fast, simple and economical method to create consistent scratch wounds on a cell monolayer.

Analyzing Tooth Germ and Trigeminal Ganglia Interactions Using a Microfluidic Co-culture System

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2025

This video demonstrates the utilization of a microfluidic device to study the interactions between tooth germ pulp and trigeminal ganglia. It showcases the placement of tissues inside the microfluidic device and provides a detailed visualization of trigeminal neurite growth toward the tooth germ through the device's microgrooves. Additionally, it highlights the role of tooth-derived molecular factors in promoting or inhibiting neurite extension into the tooth germ pulp, which is crucial for...

Education

JoVE Core - Anatomy and Physiology

Tooth Anatomy

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2024

The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth. The Crown, Neck, and Root The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.

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