Hyperlipidemia
Hyperlipidemia - Related Videos
03:42
A Murine Model of Hyperlipidemia-Induced Heart Failure with Preserved Ejection Fraction
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Cited by 2 •
2024
This protocol presents a detailed approach to replicating a murine model of hyperlipidemia-induced heart failure with preserved ejection fraction (HFpEF). The design combines the administration of adeno-associated virus 9-cardiac troponin T-low-density lipoprotein receptor (AAV9-cTnT-LDLR) and poloxamer-407 (P-407).
11:06
Network Pharmacology Prediction and Metabolomics Validation of the Mechanism of Fructus Phyllanthi against Hyperlipidemia
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Cited by 11 •
2023
The present protocol describes an integrated strategy for exploring the key targets and mechanisms of Fructus Phyllanthi against hyperlipidemia based on network pharmacology prediction and metabolomics verification.
07:57
Imaging and Analysis of Oil Red O-Stained Whole Aorta Lesions in an Aneurysm Hyperlipidemia Mouse Model
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Cited by 7 •
2022
This protocol provides a step-by-step procedure to analyze atherosclerotic burden in mice. Investigators can use this protocol to compare the abundance, location, and size of atherosclerotic lesions in different animals.
03:05
Influence of Emotional Factors on the Efficacy of Acupuncture Treatment for Overweight Complicated with Hyperlipidemia: A Retrospective Cohort Study
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2025
This protocol details the acupuncture procedures for patients with overweight complicated by hyperlipidemia and certifies the influence of emotional factors on therapeutic efficacy based on metrics including BMI, cholesterol, and triglyceride levels.
07:39
Cardiac Exam I: Inspection and Palpation
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2023
Source: Suneel Dhand, MD, Attending Physician, Internal Medicine, Beth Israel Deaconess Medical Center The cardiac assessment is one of the core examinations performed by almost every physician whenever encountering a patient. Disorders of the cardiac system are among the most common reasons for hospital admission, with conditions ranging from myocardial infarction to congestive heart failure. Learning a complete and thorough cardiac examination is therefore crucial for any practicing physician.
FAQs
The body must balance how lipids are produced, absorbed, transported, and cleared from the bloodstream. Disruption at any of these stages can cause cholesterol or triglycerides to accumulate in circulation. This systems-level view helps clinicians consider hyperlipidemia as more than a single laboratory abnormality and supports treatment strategies aimed at improving overall lipid handling.
Low-density lipoprotein cholesterol can move into and accumulate within arterial walls. That accumulation promotes plaque formation, which contributes to atherosclerosis, or narrowing and disease of the arteries. Because this process can undermine vascular health and increase cardiovascular risk, LDL cholesterol is an important focus of clinical risk assessment and lipid management.
A lipid assessment considers both cholesterol fractions and triglycerides rather than relying on a single total value. These measurements describe different aspects of circulating lipid status and can reveal distinct patterns of abnormality. Reviewing the complete profile gives clinicians a broader basis for evaluating cardiovascular risk and selecting an appropriate management approach.
A lipid panel measures cholesterol fractions and triglycerides in a blood sample. Clinicians use these results to characterize a patient's lipid status, support cardiovascular risk assessment, and help guide treatment decisions. The panel therefore connects laboratory findings with practical care planning, including consideration of lifestyle measures, weight control, and lipid-lowering medication.
Management may include dietary changes, lifestyle modification, and weight control. These approaches address modifiable contributors to abnormal lipid levels and support efforts to improve long-term vascular health. In clinical care, they may form part of a broader plan that also uses lipid-lowering medication when appropriate, with the overall aim of reducing cardiovascular events.
Lipid-lowering medications can complement dietary and lifestyle measures when clinicians are working to reduce abnormal lipid levels and cardiovascular risk. Their use is guided by clinical evaluation, including lipid-panel findings and overall risk assessment. Combining treatment approaches focuses care on lowering the likelihood of cardiovascular events while supporting sustained vascular health over time.