Drug Delivery Device

A drug delivery device is a tool engineered to administer a therapeutic substance to the body in a controlled, targeted, or sustained manner, helping improve treatment effectiveness and patient safety. Depending on its design, the device may release medication through routes such as injection, inhalation, transdermal absorption, or localized implantation, using mechanisms that regulate dose, timing, and tissue exposure. In medicine, these devices support therapies ranging from insulin delivery and inhaled treatments to implantable systems for long-term drug release. Their development can reduce dosing frequency, limit systemic side effects, and improve adherence while enabling more precise treatment of complex diseases.

Drug Delivery Device - Related Videos

Research

JoVE EoE - Neurotherapeutics

Intranasal Delivery of siRNA to the Mouse Brain Using a Positioning Device

0 Views •

2025

Source: Ullah, I., et.al. A Positioning Device for the Placement of Mice During Intranasal siRNA Delivery to the Central Nervous System. J. Vis. Exp. (2019)This video demonstrates a precise intranasal administration technique for delivering neuron-targeting peptide-siRNA complexes to the mouse brain using a specialized positioning device. Anesthetized mice are secured in a head-down-and-forward position to optimize siRNA inhalation while preventing lung drainage. The targeting peptide...

Education

JoVE Core - Pharmacokinetics and Pharmacodynamics

Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices

0 Views •

2026

Parenteral drug delivery systems play a crucial role in modern therapeutics by enabling the direct administration of drugs into the systemic circulation, bypassing the gastrointestinal tract. These systems are particularly valuable for poorly absorbed oral medications that are unstable in the digestive environment or require rapid onset or sustained therapeutic levels. Delivery is achieved through intravenous, intramuscular, or subcutaneous routes, each selected based on the drug's properties...

Ophthalmic Drug Delivery for Noninvasive Neuromodulation in a Mouse Model

0 Views •

2025

Source: Zhan, J., et al. Non-invasive Strategies for Chronic Manipulation of DREADD-controlled Neuronal Activity. J. Vis. Exp. (2019)This video demonstrates a non-invasive ophthalmic drug delivery method for targeted neuromodulation. The drug is delivered via eye drops, absorbed into the circulation, crosses the blood-brain barrier, and activates specific neuronal receptors.

Intraluminal Drug Delivery to the Mouse Arteriovenous Fistula Endothelium

0 Views •

Cited by 5 •

2016

After puncturing the aorta through the inferior vena cava (IVC) to create an aorto-caval fistula in the mouse, solution containing a drug is infused into the IVC via the same needle, followed by incubation. This method enables more robust drug delivery to the venous endothelium compared to the external route.

Manufacture and Drug Delivery Applications of Silk Nanoparticles

0 Views •

Cited by 49 •

2016

Nanoparticles are emerging as promising drug delivery systems for a broad range of indications. Here, we describe a simple yet powerful method to manufacture silk nanoparticles using reverse engineered Bombyx mori silk. These silk nanoparticles can be readily loaded with a therapeutic payload and subsequently explored for drug delivery applications.

View All Results

FAQs

Related Topics