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Intraluminal Drug Delivery to the Mouse Arteriovenous Fistula Endothelium
 

Intraluminal Drug Delivery to the Mouse Arteriovenous Fistula Endothelium

Article DOI: 10.3791/53905
March 4th, 2016

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Summary March 4th, 2016

After puncturing the aorta through the inferior vena cava (IVC) to create an aorto-caval fistula in the mouse, solution containing a drug is infused into the IVC via the same needle, followed by incubation. This method enables more robust drug delivery to the venous endothelium compared to the external route.

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