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Intraluminal Drug Delivery to the Mouse Arteriovenous Fistula Endothelium
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Intraluminal Drug Delivery to the Mouse Arteriovenous Fistula Endothelium

Intraluminal Drug Delivery to the Mouse Arteriovenous Fistula Endothelium

DOI:
10.3791/53905-v

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05:53 min

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March 04, 2016

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Chapters

  • 00:05Title
  • 00:48Intraluminal Drug Delivery
  • 04:19Results: Adenovirus-GFP Delivery to the AVF Lumen Enhances GFP Expression
  • 05:28Conclusion

Summary

Automatic Translation

Automatic Translation

After puncturing the aorta through the inferior vena cava (IVC) to create an aorto-caval fistula in the mouse, solution containing a drug is infused into the IVC via the same needle, followed by incubation. This method enables more robust drug delivery to the venous endothelium compared to the external route.

Tags

Keywords: Intraluminal Drug DeliveryMouse Arteriovenous FistulaEndotheliumVenous RemodelingNeointimal HyperplasiaSurgical ProcedureAortaIVCMicrosurgeryDrug Infusion

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