Fetal Growth

Fetal growth is the progressive increase in a developing fetus’s size, mass, and organ maturity during pregnancy, making it a key indicator of prenatal health. It depends on coordinated cell proliferation and differentiation, shaped by genetic factors and the delivery of oxygen and nutrients through the placenta; maternal health and the intrauterine environment can alter this trajectory. In medicine, clinicians assess growth using ultrasound measurements, estimated fetal weight, and growth charts to identify normal development, growth restriction, or excessive growth. These assessments support risk evaluation, monitoring, and care decisions while advancing understanding of placental function and maternal influences on neonatal health.

Fetal Growth - Related Videos

Research

JoVE Journal - Medicine

Fetal Echocardiography and Pulsed-wave Doppler Ultrasound in a Rabbit Model of Intrauterine Growth Restriction

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Cited by 11 •

2013

We describe examination of fetal cardiac function with contemporary functional fetal echocardiography and fetoplacental Doppler ultrasound using the VisualSonics VEVO 2100 microultrasound in a surgically induced model of intrauterine fetal growth restriction in a rabbit.

Murine Fetal Echocardiography

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Cited by 7 •

2013

Fetal and perinatal death is a common feature when studying genetic alterations affecting cardiac development. High-frequency ultrasound imaging has improved 2-D resolution and can provide excellent information on early cardiac development and is an ideal method to detect the impact on cardiac structure and function prior to death.

An Experimental System to Study Mechanotransduction in Fetal Lung Cells

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Cited by 7 •

2012

Mechanical forces play a key role in lung development and lung injury. Here, we describe a method to isolate rodent fetal lung type II epithelial cells and fibroblasts and to expose them to mechanical stimulation using an in vitro system.

Transuterine Fetal Tracheal Occlusion Model in Mice

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Cited by 2 •

2021

Various animal models of congenital diaphragmatic hernia and fetal tracheal occlusion present advantages and disadvantages regarding ethical issues, cost, surgical difficulty, size, survival rates, and availability of genetic tools. This model provides a new tool to study the impact of both tracheal occlusion and increased luminal pressure on lung development.

Progenitor-derived Oligodendrocyte Culture System from Human Fetal Brain

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Cited by 38 •

2012

Primary, human fetal brain-derived, multipotential progenitor cells proliferate in vitro while maintaining the capacity to differentiate into neurons and astrocytes. This work shows that neural progenitors can be induced to differentiate through stages of the oligodendrocytic lineage by conditioning with select growth factors.

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